Johanne Kongstad1, Christian Enevold2, Lisa Bøge Christensen1, Nils-Erik Fiehn3, Palle Holmstrup1. 1. Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. 2. Department of Infectious Diseases and Rheumatology, Institute for Inflammation Research, Copenhagen University Hospital, Copenhagen, Denmark. 3. Department of International Health, Immunology, and Microbiology; Faculty of Health and Medical Sciences; University of Copenhagen.
Abstract
BACKGROUND: Associations of risk factors/indicators with periodontitis may depend on the included case criterion. The objective of the current study is to evaluate differences in outcome by applying five periodontitis case definitions for cross-sectional associations with lifestyle factors among participants of the Danish Health Examination Survey (DANHES). METHODS: A total of 4,402 adults aged 18 to 96 years from the general health examination of DANHES had a periodontal examination consisting of half-mouth registration at six sites per tooth including probing depth (PD) and clinical attachment level (CAL). Periodontitis was defined according to severe periodontitis, European Workshop of Periodontology (EWP)-specific, meanCAL ≥2.55 mm, CAL-tertile, and PD-CAL definitions. Multivariable logistic regression models fitted the association of age, sex, smoking status, diabetes mellitus, educational level, alcohol consumption, body mass index, physical activity, body fat percentage, waist circumference, triglycerides, total cholesterol, and C-reactive protein with periodontitis. RESULTS: Number of cases captured by the five periodontitis case definitions ranged from 337 (9.2%) to 1,136 (31.0%). A total of 224 participants were defined as periodontitis cases by all five criteria. Analyses on 3,665 participants with complete data revealed statistically significant associations of age and smoking with all periodontitis case definitions and of male sex with severe periodontitis and EWP-specific definitions. Educational level (two lowest groups) was related to three periodontitis criteria. Among obesity and hyperlipidemia measures no factors were related to periodontitis. CONCLUSION: Regression analyses showed little difference in odds ratio across the five periodontitis case definitions; however, the level of significance did show some variation.
BACKGROUND: Associations of risk factors/indicators with periodontitis may depend on the included case criterion. The objective of the current study is to evaluate differences in outcome by applying five periodontitis case definitions for cross-sectional associations with lifestyle factors among participants of the Danish Health Examination Survey (DANHES). METHODS: A total of 4,402 adults aged 18 to 96 years from the general health examination of DANHES had a periodontal examination consisting of half-mouth registration at six sites per tooth including probing depth (PD) and clinical attachment level (CAL). Periodontitis was defined according to severe periodontitis, European Workshop of Periodontology (EWP)-specific, meanCAL ≥2.55 mm, CAL-tertile, and PD-CAL definitions. Multivariable logistic regression models fitted the association of age, sex, smoking status, diabetes mellitus, educational level, alcohol consumption, body mass index, physical activity, body fat percentage, waist circumference, triglycerides, total cholesterol, and C-reactive protein with periodontitis. RESULTS: Number of cases captured by the five periodontitis case definitions ranged from 337 (9.2%) to 1,136 (31.0%). A total of 224 participants were defined as periodontitis cases by all five criteria. Analyses on 3,665 participants with complete data revealed statistically significant associations of age and smoking with all periodontitis case definitions and of male sex with severe periodontitis and EWP-specific definitions. Educational level (two lowest groups) was related to three periodontitis criteria. Among obesity and hyperlipidemia measures no factors were related to periodontitis. CONCLUSION: Regression analyses showed little difference in odds ratio across the five periodontitis case definitions; however, the level of significance did show some variation.
Authors: Daniel Belstrøm; Josefine Maria Eiberg; Christian Enevold; Maria Anastasia Grande; Claus Antonio Juel Jensen; Lone Skov; Peter Riis Hansen Journal: Oral Dis Date: 2020-01-28 Impact factor: 3.511
Authors: Daniel Belstrøm; Florentin Constancias; Daniela I Drautz-Moses; Stephan C Schuster; Mark Veleba; Frédéric Mahé; Michael Givskov Journal: NPJ Biofilms Microbiomes Date: 2021-09-23 Impact factor: 7.290