Literature DB >> 28128057

Muscle Coordination and Locomotion in Humans.

Francesca Sylos-Labini1, Myrka Zago2, Pierre A Guertin3, Francesco Lacquaniti4, Yury P Ivanenko2.   

Abstract

Locomotion is a semi-automatic daily task. Several studies show that muscle activity is fairly stereotyped during normal walking. Nevertheless, each human leg contains over 50 muscles and locomotion requires flexibility in order to adapt to different conditions as, for instance, different speeds, gaits, turning, obstacle avoidance, altered gravity levels, etc. Therefore, locomotor control has to deal with a certain level of flexibility and non-linearity. In this review, we describe and discuss different findings dealing with both simplicity and variability of the muscular control, as well as with its maturation during development. Despite complexity and redundancy, muscle activity patterns and spatiotemporal maps of spinal motoneuron output during human locomotion show both stereotypical features as well as functional re-organization. Flexibility and different solutions to adjust motor patterns should be considered when considering new rehabilitation strategies to treat disorders involving deficits in gait. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Muscle activity; basic activation patterns; central pattern generator; human locomotion; spinal locomotor output

Mesh:

Year:  2017        PMID: 28128057     DOI: 10.2174/1381612823666170125160820

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  2 in total

Review 1.  Gait analysis under the lens of statistical physics.

Authors:  Massimiliano Zanin; Felipe Olivares; Irene Pulido-Valdeolivas; Estrella Rausell; David Gomez-Andres
Journal:  Comput Struct Biotechnol J       Date:  2022-06-18       Impact factor: 6.155

Review 2.  Advances in single-cell sequencing and its application to musculoskeletal system research.

Authors:  Yongxiang Zhang; Jingkai Wang; Chao Yu; Kaishun Xia; Biao Yang; Yuang Zhang; Liwei Ying; Chenggui Wang; Xianpeng Huang; Qixin Chen; Li Shen; Fangcai Li; Chengzhen Liang
Journal:  Cell Prolif       Date:  2021-12-09       Impact factor: 6.831

  2 in total

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