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Literature DB >> 28127990

Animal models suggest the TRIP8b-HCN interaction is a therapeutic target for major depressive disorder.

Kyle A Lyman¹, Ye Han¹, Dane M Chetkovich¹.

Abstract

Entities: Chemical Disease Gene Mutation Species

Keywords: HCN; Pex5; TRIP8b; depression; ion channel

Mesh：

Substances：

Year: 2017 PMID： 28127990 PMCID： PMC5546004 DOI： 10.1080/14728222.2017.1287899

Source DB: PubMed Journal: Expert Opin Ther Targets ISSN： 1472-8222 Impact factor: 6.902

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15 in total

Review 1. Peroxisome targeting signal 1: is it really a simple tripeptide?

Authors: Cécile Brocard; Andreas Hartig
Journal: Biochim Biophys Acta Date: 2006-08-24

Review 2. HCN channels: structure, cellular regulation and physiological function.

Authors: C Wahl-Schott; M Biel
Journal: Cell Mol Life Sci Date: 2009-02 Impact factor: 9.261

3. Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.

Authors: Ye Han; Kyle Lyman; Matt Clutter; Gary E Schiltz; Quratul-Ain Ismail; Diego Bleifuss Prados; Chi-Hao Luan; Dane M Chetkovich
Journal: J Biomol Screen Date: 2015-06-04

4. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.

Authors: Andrea Saponaro; Sofia R Pauleta; Francesca Cantini; Manolis Matzapetakis; Christian Hammann; Chiara Donadoni; Lei Hu; Gerhard Thiel; Lucia Banci; Bina Santoro; Anna Moroni
Journal: Proc Natl Acad Sci U S A Date: 2014-09-02 Impact factor: 11.205

5. TRIP8b regulates HCN1 channel trafficking and gating through two distinct C-terminal interaction sites.

Authors: Bina Santoro; Lei Hu; Haiying Liu; Andrea Saponaro; Phillip Pian; Rebecca A Piskorowski; Anna Moroni; Steven A Siegelbaum
Journal: J Neurosci Date: 2011-03-16 Impact factor: 6.167

6. Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.

Authors: John R Bankston; Stacey S Camp; Frank DiMaio; Alan S Lewis; Dane M Chetkovich; William N Zagotta
Journal: Proc Natl Acad Sci U S A Date: 2012-05-01 Impact factor: 11.205

7. Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.

Authors: Alan S Lewis; Sachin P Vaidya; Cory A Blaiss; Zhiqiang Liu; Travis R Stoub; Darrin H Brager; Xiangdong Chen; Roland A Bender; Chad M Estep; Andrey B Popov; Catherine E Kang; Paul P Van Veldhoven; Douglas A Bayliss; Daniel A Nicholson; Craig M Powell; Daniel Johnston; Dane M Chetkovich
Journal: J Neurosci Date: 2011-05-18 Impact factor: 6.167

8. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience.

Authors: Allyson K Friedman; Jessica J Walsh; Barbara Juarez; Stacy M Ku; Dipesh Chaudhury; Jing Wang; Xianting Li; David M Dietz; Nina Pan; Vincent F Vialou; Rachael L Neve; Zhenyu Yue; Ming-Hu Han
Journal: Science Date: 2014-04-18 Impact factor: 47.728

9. Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.

Authors: Robert J Heuermann; Thomas C Jaramillo; Shui-Wang Ying; Benjamin A Suter; Kyle A Lyman; Ye Han; Alan S Lewis; Thomas G Hampton; Gordon M G Shepherd; Peter A Goldstein; Dane M Chetkovich
Journal: Neurobiol Dis Date: 2015-10-14 Impact factor: 5.996

10. TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons.

Authors: Rebecca Piskorowski; Bina Santoro; Steven A Siegelbaum
Journal: Neuron Date: 2011-05-12 Impact factor: 17.173

13 in total

1. HCN channels in the hippocampus regulate active coping behavior.

Authors: Daniel W Fisher; Ye Han; Kyle A Lyman; Robert J Heuermann; Linda A Bean; Natividad Ybarra; Kendall M Foote; Hongxin Dong; Daniel A Nicholson; Dane M Chetkovich
Journal: J Neurochem Date: 2018-08-09 Impact factor: 5.372

2. Neuroinflammation Alters Integrative Properties of Rat Hippocampal Pyramidal Cells.

Authors: Federica Frigerio; Corey Flynn; Ye Han; Kyle Lyman; Joaquin N Lugo; Teresa Ravizza; Antoine Ghestem; Julika Pitsch; Albert Becker; Anne E Anderson; Annamaria Vezzani; Dane Chetkovich; Christophe Bernard
Journal: Mol Neurobiol Date: 2018-02-09 Impact factor: 5.590

Review 3. Current Opinions and Consensus for Studying Tremor in Animal Models.

Authors: Sheng-Han Kuo; Elan D Louis; Phyllis L Faust; Adrian Handforth; Su-Youne Chang; Billur Avlar; Eric J Lang; Ming-Kai Pan; Lauren N Miterko; Amanda M Brown; Roy V Sillitoe; Collin J Anderson; Stefan M Pulst; Martin J Gallagher; Kyle A Lyman; Dane M Chetkovich; Lorraine N Clark; Murni Tio; Eng-King Tan; Rodger J Elble
Journal: Cerebellum Date: 2019-12 Impact factor: 3.847

4. Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior.

Authors: Kyle A Lyman; Ye Han; Chengwen Zhou; Isabelle Renteria; Gai-Linn Besing; Jonathan E Kurz; Dane M Chetkovich
Journal: Sci Transl Med Date: 2021-11-24 Impact factor: 19.319

5. Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels.

Authors: Kyle A Lyman; Ye Han; Robert J Heuermann; Xiangying Cheng; Jonathan E Kurz; Reagan E Lyman; Paul P Van Veldhoven; Dane M Chetkovich
Journal: J Biol Chem Date: 2017-09-08 Impact factor: 5.157

6. Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu₃) impairs postsynaptic plasticity and modulates affective behaviors.

Authors: Max E Joffe; Chiaki I Santiago; Sheryl Anne D Vermudez; Nicole M Fisher; Shalini Dogra; Colleen M Niswender; P Jeffrey Conn
Journal: Neuropsychopharmacology Date: 2021-05-25 Impact factor: 7.853