| Literature DB >> 28127603 |
Chenfu Liu1, Chao Yang2, Lihua Lu3, Wanhe Wang1, Weihong Tan4, Chung-Hang Leung2, Dik-Lung Ma1.
Abstract
Two luminescent iridium(iii) complexes, 1 and 2, were synthesized and evaluated for their ability to probe COX-2 in human cancer cells. This is the first application of iridium(iii) complexes as imaging agents for COX-2. We demonstrate that complex 1 differentiates cancer cells from normal cells with high stability and low cytotoxicity.Entities:
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Year: 2017 PMID： 28127603 DOI： 10.1039/c6cc08109f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222