Literature DB >> 28127591

Tasty THC: Promises and Challenges of Cannabis Edibles.

Daniel G Barrus1, Kristen L Capogrossi1, Sheryl C Cates1, Camille K Gourdet1, Nicholas C Peiper1, Scott P Novak1, Timothy W Lefever1, Jenny L Wiley1.   

Abstract

Food products containing cannabis extract (edibles) have emerged as a popular and lucrative facet of the legalized market for both recreational and medicinal cannabis. The many formulations of cannabis extracts used in edibles present a unique regulatory challenge for policy makers. Though edibles are often considered a safe, discreet, and effective means of attaining the therapeutic and/or intoxicating effects of cannabis without exposure to the potentially harmful risks of cannabis smoking, little research has evaluated how ingestion differs from other methods of cannabis administration in terms of therapeutic efficacy, subjective effects, and safety. The most prominent difference between ingestion and inhalation of cannabis extracts is the delayed onset of drug effect with ingestion. Consumers often do not understand this aspect of edible use and may consume a greater than intended amount of drug before the drug has taken effect, often resulting in profoundly adverse effects. Written for the educated layperson and for policy makers, this paper explores the current state of research regarding edibles, highlighting the promises and challenges that edibles present to both users and policy makers, and describes the approaches that four states in which recreational cannabis use is legal have taken regarding regulating edibles.

Entities:  

Year:  2016        PMID: 28127591      PMCID: PMC5260817          DOI: 10.3768/rtipress.2016.op.0035.1611

Source DB:  PubMed          Journal:  Methods Rep RTI Press


  77 in total

Review 1.  Blurred boundaries: the therapeutics and politics of medical marijuana.

Authors:  J Michael Bostwick
Journal:  Mayo Clin Proc       Date:  2012-02       Impact factor: 7.616

2.  THC can be detected in brain while absent in blood.

Authors:  Patrick Mura; Pascal Kintz; Véronique Dumestre; Sébastien Raul; Thierry Hauet
Journal:  J Anal Toxicol       Date:  2005 Nov-Dec       Impact factor: 3.367

Review 3.  Human cannabinoid pharmacokinetics.

Authors:  Marilyn A Huestis
Journal:  Chem Biodivers       Date:  2007-08       Impact factor: 2.408

Review 4.  Chronic toxicology of cannabis.

Authors:  Albert Stuart Reece
Journal:  Clin Toxicol (Phila)       Date:  2009-07       Impact factor: 4.467

5.  Evaluation of trends in marijuana toxicosis in dogs living in a state with legalized medical marijuana: 125 dogs (2005-2010).

Authors:  Stacy D Meola; Caitlin C Tearney; Sharlee A Haas; Timothy B Hackett; Elisa M Mazzaferro
Journal:  J Vet Emerg Crit Care (San Antonio)       Date:  2012-12

Review 6.  Structure-activity relationships in man of cannabis constituents, and homologs and metabolites of delta9-tetrahydrocannabinol.

Authors:  L E Hollister
Journal:  Pharmacology       Date:  1974       Impact factor: 2.547

Review 7.  Cancer cachexia and cannabinoids.

Authors:  R W Gorter
Journal:  Forsch Komplementarmed       Date:  1999-10

8.  Stigma among California's Medical Marijuana Patients.

Authors:  Travis D Satterlund; Juliet P Lee; Roland S Moore
Journal:  J Psychoactive Drugs       Date:  2015 Jan-Mar

9.  Marijuana Tourism and Emergency Department Visits in Colorado.

Authors:  Howard S Kim; Katelyn E Hall; Emma K Genco; Mike Van Dyke; Elizabeth Barker; Andrew A Monte
Journal:  N Engl J Med       Date:  2016-02-25       Impact factor: 91.245

10.  Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.

Authors:  Margaret Haney; Erik W Gunderson; Judith Rabkin; Carl L Hart; Suzanne K Vosburg; Sandra D Comer; Richard W Foltin
Journal:  J Acquir Immune Defic Syndr       Date:  2007-08-15       Impact factor: 3.731

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  42 in total

1.  Pharmacokinetics of Cannabis Brownies: A Controlled Examination of Δ9-Tetrahydrocannabinol and Metabolites in Blood and Oral Fluid of Healthy Adult Males and Females.

Authors:  Tory R Spindle; Edward J Cone; Evan S Herrmann; John M Mitchell; Ronald Flegel; Charles LoDico; George E Bigelow; Ryan Vandrey
Journal:  J Anal Toxicol       Date:  2020-10-12       Impact factor: 3.367

2.  Voluntary oral consumption of Δ9-tetrahydrocannabinol by adolescent rats impairs reward-predictive cue behaviors in adulthood.

Authors:  Lauren C Kruse; Jessica K Cao; Katie Viray; Nephi Stella; Jeremy J Clark
Journal:  Neuropsychopharmacology       Date:  2019-04-10       Impact factor: 7.853

3.  Trends in marijuana edible consumption and perceptions of harm in a cohort of young adults.

Authors:  Beth A Reboussin; Kimberly G Wagoner; Erin L Sutfin; Cynthia Suerken; Jennifer Cornacchione Ross; Kathleen L Egan; Stephannie Walker; Renee M Johnson
Journal:  Drug Alcohol Depend       Date:  2019-10-23       Impact factor: 4.492

Review 4.  Cannabis regulatory science: risk-benefit considerations for mental disorders.

Authors:  Jacob T Borodovsky; Alan J Budney
Journal:  Int Rev Psychiatry       Date:  2018-05-29

5.  Regulating Cannabis Manufacturing: Applying Public Health Best Practices from Tobacco Control.

Authors:  Daniel G Orenstein; Stanton A Glantz
Journal:  J Psychoactive Drugs       Date:  2018-02-13

6.  Health considerations of the legalization of cannabis edibles.

Authors:  Jasleen K Grewal; Lawrence C Loh
Journal:  CMAJ       Date:  2020-01-06       Impact factor: 8.262

Review 7.  Changing landscape of cannabis: novel products, formulations, and methods of administration.

Authors:  Tory R Spindle; Marcel O Bonn-Miller; Ryan Vandrey
Journal:  Curr Opin Psychol       Date:  2019-04-09

8.  Evaluation of reinforcing and aversive effects of voluntary Δ9-tetrahydrocannabinol ingestion in rats.

Authors:  Daniel G Barrus; Timothy W Lefever; Jenny L Wiley
Journal:  Neuropharmacology       Date:  2018-05-03       Impact factor: 5.250

9.  Complex cannabis use patterns: Associations with cannabis consequences and cannabis use disorder symptomatology.

Authors:  Rachel L Gunn; Elizabeth R Aston; Alexander W Sokolovsky; Helene R White; Kristina M Jackson
Journal:  Addict Behav       Date:  2020-01-30       Impact factor: 3.913

10.  Legal cannabis laws, home cultivation, and use of edible cannabis products: A growing relationship?

Authors:  Jacob T Borodovsky; Alan J Budney
Journal:  Int J Drug Policy       Date:  2017-11-05
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