Literature DB >> 28126579

Sleep disturbances in individuals at clinical high risk for psychosis.

Sarah-Lucy Poe1, Gary Brucato2, Nicolina Bruno2, Leigh Y Arndt2, Shelly Ben-David2, Kelly E Gill2, Tiziano Colibazzi2, Joshua T Kantrowitz2, Cheryl M Corcoran2, Ragy R Girgis2.   

Abstract

There has been recent interest in understanding the role that sleep disturbance plays in patients at Clinical High Risk for psychosis (CHR). We assessed sleep disturbance in 194 CHR patients and 66 healthy control subjects and their relationship to symptoms (positive, negative and general functioning). Patients experienced significantly more sleep disturbance than healthy control subjects and their sleep disturbance was related to greater positive and negative symptoms and worse overall functioning. Targeting sleep disturbance in CHR individuals may provide alternative means of treating the CHR syndrome.
Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Clinical/Ultra high risk; Prodromal; Psychosis; Sleep Disturbance

Mesh：

Year:  2016        PMID： 28126579      PMCID： PMC5893278          DOI： 10.1016/j.psychres.2016.12.029

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


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