Anneleen Maris1, Karin Coninx2, Henk Seelen3, Veronik Truyens4, Tom De Weyer2, Richard Geers3, Mieke Lemmens4, Jolijn Coolen4, Sandra Stupar3, Ilse Lamers1, Peter Feys1. 1. a Faculty of Medicine and Life Sciences , REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Hasselt University , Diepenbeek , Belgium. 2. b Expertise Centre for Digital Media - tUL - iMinds, Hasselt University , Diepenbeek , Belgium. 3. c Adelante Centre of Expertise in Rehabilitation and Audiology , Hoensbroek , The Netherlands. 4. d Rehabilitation and MS Center , Overpelt , Belgium.
Abstract
PURPOSE: The current study aimed to investigate proof-of-concept efficacy of an individualized, robot-mediated training regime for people with MS (pwMS) and stroke patients. METHOD: Thirteen pwMS and 14 chronic stroke patients performed 36 (stroke) or 40 (pwMS) training sessions with the I-TRAVLE system. Evaluation of upper limb function was performed at baseline, after training and at 3 months follow-up. Clinical outcome measures consisted of active range of motion (ROM), Motricity Index, Jamar handgrip strength, perceived fatigue and strength, Wolf Motor Function Test (WFMT) and ABILHAND. Robot-generated outcome measures consisted of movement velocity, ROM and actual covered distance compared to straight-line distance. RESULTS: In pwMS, significant improvements were found after training in active shoulder ROM, handgrip strength, perceived strength and WMFT activities. No significant change in clinical outcome was found in stroke patients, except for perceived strength. Significant improvement in speed and movement duration was found after training in both groups. At follow-up, clinical outcome deteriorated in pwMS and was maintained in stroke patients. CONCLUSIONS: Robot-mediated training resulted in improved movement coordination in both groups, as well as clinical improvement in pwMS. Absence of functional improvements in stroke patients may relate to severe upper limb dysfunction at baseline. Implications for Rehabilitation Robot-mediated training improved strength, active range of motion and upper limb capacity in pwMS. Robot-mediated therapy allows for adapted training difficulty.
PURPOSE: The current study aimed to investigate proof-of-concept efficacy of an individualized, robot-mediated training regime for people with MS (pwMS) and strokepatients. METHOD: Thirteen pwMS and 14 chronic strokepatients performed 36 (stroke) or 40 (pwMS) training sessions with the I-TRAVLE system. Evaluation of upper limb function was performed at baseline, after training and at 3 months follow-up. Clinical outcome measures consisted of active range of motion (ROM), Motricity Index, Jamar handgrip strength, perceived fatigue and strength, Wolf Motor Function Test (WFMT) and ABILHAND. Robot-generated outcome measures consisted of movement velocity, ROM and actual covered distance compared to straight-line distance. RESULTS: In pwMS, significant improvements were found after training in active shoulder ROM, handgrip strength, perceived strength and WMFT activities. No significant change in clinical outcome was found in strokepatients, except for perceived strength. Significant improvement in speed and movement duration was found after training in both groups. At follow-up, clinical outcome deteriorated in pwMS and was maintained in strokepatients. CONCLUSIONS: Robot-mediated training resulted in improved movement coordination in both groups, as well as clinical improvement in pwMS. Absence of functional improvements in strokepatients may relate to severe upper limb dysfunction at baseline. Implications for Rehabilitation Robot-mediated training improved strength, active range of motion and upper limb capacity in pwMS. Robot-mediated therapy allows for adapted training difficulty.
Authors: Christoph M Kanzler; Ilse Lamers; Peter Feys; Roger Gassert; Olivier Lambercy Journal: Med Biol Eng Comput Date: 2021-11-25 Impact factor: 2.602