Literature DB >> 28124590

A Multicentre Italian Validation Study in Aging Adults with Down Syndrome and Other Forms of Intellectual Disabilities: Dementia Screening Questionnaire for Individuals with Intellectual Disabilities.

Tiziano Gomiero1, Marco Bertelli2, Shoumitro Deb3, Elisabeth Weger4, Annachiara Marangoni4, Elisa De Bastiani4, Ulrico Mantesso4, Luc Pieter De Vreese5.   

Abstract

BACKGROUND: The USA National Task Group (NTG) guidelines advocate the use of an adapted version of Dementia Screening Questionnaire for Individuals with Intellectual Disabilities (DSQIID) for dementia screening of individuals with Down syndrome (DS) and with other forms of ID (non-DS).
OBJECTIVE: In order to meet these guidelines, this study verifies the psychometric properties of an Italian version of the original DSQIID in a population composed of adults aged 40 years and over with DS and non-DS ID.
METHODS: Internal consistency, inter-rater and intra-rater reliabilities, structural validity, convergent validity and known group differences of DSQIID-I were assessed with 200 individuals with ID (mean of 55.2 years; range: 40-80 years) recruited from 15 different centers in Italy. Diagnosis of dementia was done according to IASSID diagnostic criteria and its degree of clinical certainty was defined according to Silverman et al.'s classification (2004).
RESULTS: Cronbach's alpha for the DSQIID-I was 0.94. The ICCs for inter-rater and test-retest reliability were both 0.89. A Principal Component analysis revealed three domains, namely memory and confusion- related items, motor and functional disabilities, depression and apathy, which explained almost 40% of the overall variance. The total DSQIID-I score correlated significantly with DMR and differed significantly among those individuals (n = 34) with cognitive decline from those without (n = 166). Age, gender and severity of ID were unrelated to the DSQIID-I.
CONCLUSION: The present study confirms the cross-cultural value of DSQIID which was proved to be a psychometrically valid and user-friendly observer-rated scale for dementia screening in adults with both DS and non-DS ID. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Alzheimer's disease (AD); dementia; intellectual disability; psychometric properties; screening test; validation

Mesh:

Year:  2017        PMID: 28124590     DOI: 10.2174/1567205014666170117094757

Source DB:  PubMed          Journal:  Curr Alzheimer Res        ISSN: 1567-2050            Impact factor:   3.498


  3 in total

1.  Microstate Changes Associated With Alzheimer's Disease in Persons With Down Syndrome.

Authors:  Christian Sandøe Musaeus; Lise Cronberg Salem; Troels Wesenberg Kjaer; Gunhild Waldemar
Journal:  Front Neurosci       Date:  2019-11-28       Impact factor: 4.677

2.  Adaptation of the Clinical Dementia Rating Scale for adults with Down syndrome.

Authors:  Christina N Lessov-Schlaggar; Olga L Del Rosario; John C Morris; Beau M Ances; Bradley L Schlaggar; John N Constantino
Journal:  J Neurodev Disord       Date:  2019-12-16       Impact factor: 4.025

3.  Anticholinergic burden in adult and elderly people with intellectual disabilities: Results from an Italian multicenter cross-sectional study.

Authors:  Luc Pieter De Vreese; Ulrico Mantesso; Elisa De Bastiani; Annachiara Marangoni; Elisabeth Weger; Tiziano Gomiero
Journal:  PLoS One       Date:  2018-10-31       Impact factor: 3.240

  3 in total

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