Literature DB >> 2812245

The use of hollow polymer fibers for the delivery of bioactive molecules to the brain.

J E Springer1.   

Abstract

Experimental studies have provided evidence that bioactive molecules can be delivered to the central nervous system through the use of hollow polymer fibers. These implantable fibers can be used for the delivery of peptide solutions or serve as a carrier device for encapsulating tissue preparations and cell suspensions. This commentary will address the use of these polymer fibers as a potential therapeutic strategy for treating neurodegenerative disorders such as Alzheimer's disease.

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Year:  1989        PMID: 2812245     DOI: 10.1016/0197-4580(89)90163-2

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN: 0197-4580            Impact factor:   4.673


  1 in total

1.  Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.

Authors:  Carla Hassler; Yanan Zhang; Brian Gilmour; Tyler Graf; Timothy Fennell; Rodney Snyder; Jeffrey R Deschamps; Rainer K Reinscheid; Celia Garau; Scott P Runyon
Journal:  ACS Chem Neurosci       Date:  2014-07-11       Impact factor: 4.418

  1 in total

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