Literature DB >> 28122199

Current meningitis outbreak in Ghana: Historical perspectives and the importance of diagnostics.

Alexander Kwarteng1, John Amuasi2, Augustina Annan3, Samuel Ahuno4, David Opare5, Michael Nagel6, Christof Vinnemeier7, Jürgen May8, Ellis Owusu-Dabo9.   

Abstract

Bacterial meningitis continues to be one of the most dreaded infections in sub-Saharan Africa and other countries that fall in the "meningitis belt" due to recurrent nature of the infection and the sequel of deliberating effects among survivors even after treatment. Ghana has had recurrent epidemics in the past but has been free from high mortality levels. Whereas reasons for the low reported number of deaths in the past are unclear, we hypothesize that it may be due to increased vaccination from expanded program on immunization (EPI) and consequent herd immunity of the general population. As at the end of February, 2016, 100 individuals were reported to have died out of 500 recorded cases. The infection may cause severe brain damage and kills at least 1 out of 10 individuals if quick interventions are not provided. The Ghana Health Service (GHS) and the Ministry of Health (MoH), together with other local and international stakeholders are working intensely to control the spread of the infection in affected communities with treatment and other health management programmes. This review presents a quick overview of meningitis in Ghana with emphasis on S. pneumoniae (responsible for about 70% of cases in the recent epidemic) together with some recommendations aimed at ensuring a "meningitis-free Ghana".
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antibiotics; Ghana; Meningitis; Serotype; Streptococcus pneumoniae; Vaccine

Mesh:

Substances:

Year:  2017        PMID: 28122199     DOI: 10.1016/j.actatropica.2017.01.014

Source DB:  PubMed          Journal:  Acta Trop        ISSN: 0001-706X            Impact factor:   3.112


  4 in total

1.  Diagnosis of bacterial meningitis in Ghana: Polymerase chain reaction versus latex agglutination methods.

Authors:  Nafiu Amidu; Benedict Boateng Antuamwine; Otchere Addai-Mensah; Abass Abdul-Karim; Azure Stebleson; Braimah Baba Abubakari; John Abenyeri; Afia Serwaa Opoku; John Eyulaku Nkukah; Ali Sidi Najibullah
Journal:  PLoS One       Date:  2019-01-17       Impact factor: 3.240

2.  Preponderance of vaccine-preventable diseases hotspots in northern Ghana: a spatial and space-time clustering analysis from 2010 to 2014.

Authors:  Daniel Amoako-Sakyi; Dorcas Obiri-Yeboah; Anthony Ofosu; Kwadwo Asamoah Kusi; Kingsley Osei; Richard Adade; Ebenezer Aniakwaa-Bonsu; Reginald Quansah; John Arko-Mensah; Brodrick Yeboah Amoah; Godwin Kwakye-Nuako; Eric Yaw Frimpong; Mariama Combasseré-Cherif; Hidaya Mohammed; Boubacar Maiga; Julius Fobil; Isabella Quakyi; Ben A Gyan
Journal:  BMC Public Health       Date:  2022-10-12       Impact factor: 4.135

3.  Declining Trends of Pneumococcal Meningitis in Gambian Children After the Introduction of Pneumococcal Conjugate Vaccines.

Authors:  Bakary Sanneh; Catherine Okoi; Mary Grey-Johnson; Haddy Bah-Camara; Baba Kunta Fofana; Ignatius Baldeh; Alhagie Papa Sey; Mahamadou Labbo Bah; Mamadi Cham; Amadou Samateh; Effua Usuf; Peter Sylvanus Ndow; Madikay Senghore; Archibald Worwui; Jason M Mwenda; Brenda Kwambana-Adams; Martin Antonio
Journal:  Clin Infect Dis       Date:  2019-09-05       Impact factor: 9.079

4.  Multi-step ahead meningitis case forecasting based on decomposition and multi-objective optimization methods.

Authors:  Matheus Henrique Dal Molin Ribeiro; Viviana Cocco Mariani; Leandro Dos Santos Coelho
Journal:  J Biomed Inform       Date:  2020-09-22       Impact factor: 6.317

  4 in total

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