Literature DB >> 28121455

Biomimetic Synthesis and Structural Revision of Chaxine B and Its Analogues.

Yushi Hirata1, Atsuo Nakazaki1, Hirokazu Kawagishi2, Toshio Nishikawa1.   

Abstract

Chaxine B and its analogues were synthesized from ergosterol in eight steps on the basis of our proposed biosynthetic pathway, which includes a highly site-selective and regioselective Baeyer-Villiger oxidation as the key step. This synthesis enabled the revision of the structures of chaxine B and its analogues.

Entities:  

Year:  2017        PMID: 28121455     DOI: 10.1021/acs.orglett.6b03724

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

Review 1.  Structure and Biological Activity of Ergostane-Type Steroids from Fungi.

Authors:  Vladimir N Zhabinskii; Pavel Drasar; Vladimir A Khripach
Journal:  Molecules       Date:  2022-03-24       Impact factor: 4.411

2.  Discovery of four modified classes of triterpenoids delineated a metabolic cascade: compound characterization and biomimetic synthesis.

Authors:  Bin Zhou; Xin-Hua Gao; Min-Min Zhang; Cheng-Yu Zheng; Hong-Chun Liu; Jian-Min Yue
Journal:  Chem Sci       Date:  2021-06-18       Impact factor: 9.825

  2 in total

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