| Literature DB >> 28121452 |
Rajendra Maity1, Chandan Gharui1, Arun K Sil1, Subhas Chandra Pan1.
Abstract
An organocatalytic asymmetric cascade Michael/hemiketalization/retro-aldol reaction between unsaturated pyrazolones and α-nitroketones is described. A bifunctional thiourea catalyst was found to be efficient for this reaction. With 10 mol % of catalyst, high yields as well as excellent enantioselectivities are attained for a variety of 3-acyloxy pyrazoles under mild reaction conditions.Entities:
Year: 2017 PMID： 28121452 DOI： 10.1021/acs.orglett.6b03823
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005