Literature DB >> 28120042

Recent advances in epilepsy.

Mark Manford1.   

Abstract

This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy's broader comorbidity, especially depression.

Entities:  

Keywords:  Classification; Epilepsy; Epileptogenesis; Pregnancy; Status epilepticus; Treatment

Mesh:

Year:  2017        PMID: 28120042      PMCID: PMC5533817          DOI: 10.1007/s00415-017-8394-2

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  184 in total

Review 1.  Antidepressant drugs: indications and guidelines for use in epilepsy.

Authors:  Bettina Schmitz
Journal:  Epilepsia       Date:  2002       Impact factor: 5.864

2.  De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy.

Authors:  L Claes; J Del-Favero; B Ceulemans; L Lagae; C Van Broeckhoven; P De Jonghe
Journal:  Am J Hum Genet       Date:  2001-05-15       Impact factor: 11.025

3.  A PROPOSED INTERNATIONAL CLASSIFICATION OF EPILEPTIC SEIZURES.

Authors:  E N ARNAUTOVA; T N NESMEIANOVA
Journal:  Epilepsia       Date:  1964-12       Impact factor: 5.864

4.  Medical genetics: a marker for Stevens-Johnson syndrome.

Authors:  Wen-Hung Chung; Shuen-Iu Hung; Hong-Shang Hong; Mo-Song Hsih; Li-Cheng Yang; Hsin-Chun Ho; Jer-Yuarn Wu; Yuan-Tsong Chen
Journal:  Nature       Date:  2004-04-01       Impact factor: 49.962

5.  Trafficking of GABA(A) receptors, loss of inhibition, and a mechanism for pharmacoresistance in status epilepticus.

Authors:  David E Naylor; Hantao Liu; Claude G Wasterlain
Journal:  J Neurosci       Date:  2005-08-24       Impact factor: 6.167

6.  Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels.

Authors:  A D Wickenden; W Yu; A Zou; T Jegla; P K Wagoner
Journal:  Mol Pharmacol       Date:  2000-09       Impact factor: 4.436

Review 7.  Mood disorders in patients with epilepsy: epidemiology and management.

Authors:  Cynthia L Harden; Martin A Goldstein
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

8.  Early identification of refractory epilepsy.

Authors:  P Kwan; M J Brodie
Journal:  N Engl J Med       Date:  2000-02-03       Impact factor: 91.245

9.  A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology.

Authors:  J Engel
Journal:  Epilepsia       Date:  2001-06       Impact factor: 5.864

10.  Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy.

Authors:  L S Boylan; L A Flint; D L Labovitz; S C Jackson; K Starner; O Devinsky
Journal:  Neurology       Date:  2004-01-27       Impact factor: 9.910

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  43 in total

1.  The ketogenic diet increases Neuregulin 1 expression via elevating histone acetylation and its anti-seizure effect requires ErbB4 kinase activity.

Authors:  Jin Wang; Jie Huang; Shan Yao; Jia-Hui Wu; Hui-Bin Li; Feng Gao; Ying Wang; Guo-Bin Huang; Qiang-Long You; Jianhua Li; Xiaohui Chen; Xiang-Dong Sun
Journal:  Cell Biosci       Date:  2021-05-21       Impact factor: 7.133

Review 2.  Performance of PET imaging for the localization of epileptogenic zone in patients with epilepsy: a meta-analysis.

Authors:  Na Niu; Haiqun Xing; Meiqi Wu; Yanru Ma; Yimin Liu; Jiantao Ba; Shikun Zhu; Fang Li; Li Huo
Journal:  Eur Radiol       Date:  2021-02-01       Impact factor: 5.315

3.  Capsaicin Exerts Anti-convulsant and Neuroprotective Effects in Pentylenetetrazole-Induced Seizures.

Authors:  Omar M E Abdel-Salam; Amany A Sleem; Marawan Abd El Baset Mohamed Sayed; Eman R Youness; Nermeen Shaffie
Journal:  Neurochem Res       Date:  2020-02-08       Impact factor: 3.996

4.  Potentiating α2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet syndrome.

Authors:  Toshihiro Nomura; Nicole A Hawkins; Jennifer A Kearney; Alfred L George; Anis Contractor
Journal:  J Physiol       Date:  2019-05-20       Impact factor: 5.182

5.  Computational exploration of vicine - an alkaloid glycoside mediated pathological hallmark of adenosine kinase to promote neurological disorder.

Authors:  SathishKumar Paramashivam; Suganthana Balasubramaniam; Kannan Narayanan Dhiraviam
Journal:  Metab Brain Dis       Date:  2021-01-26       Impact factor: 3.584

6.  The study of microtubule dynamics and stability at the postsynaptic density in a rat pilocarpine model of temporal lobe epilepsy.

Authors:  Xiaomei Wu; Ying Zhou; Zhiling Huang; Mingfei Cai; Yi Shu; Chang Zeng; Li Feng; Bo Xiao; Qiong Zhan
Journal:  Ann Transl Med       Date:  2020-07

7.  Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment.

Authors:  Kevin S O'Connell; Alexey Shadrin; Olav B Smeland; Shahram Bahrami; Oleksandr Frei; Francesco Bettella; Florian Krull; Chun C Fan; Ragna B Askeland; Gun Peggy S Knudsen; Anne Halmøy; Nils Eiel Steen; Torill Ueland; G Bragi Walters; Katrín Davíðsdóttir; Gyða S Haraldsdóttir; Ólafur Ó Guðmundsson; Hreinn Stefánsson; Ted Reichborn-Kjennerud; Jan Haavik; Anders M Dale; Kári Stefánsson; Srdjan Djurovic; Ole A Andreassen
Journal:  Biol Psychiatry       Date:  2019-11-29       Impact factor: 13.382

Review 8.  Pannexin-1 Channel Regulates ATP Release in Epilepsy.

Authors:  Yisi Shan; Yaohui Ni; Zhiwei Gao
Journal:  Neurochem Res       Date:  2020-03-13       Impact factor: 3.996

9.  Pregabalin as adjunctive therapy in adult and pediatric patients with generalized tonic-clonic seizures: A randomized, placebo-controlled trial.

Authors:  Joseph Driscoll; Mary Almas; Gabriela Gregorian; Alla Kyrychenko; Iryna Makedonska; Jing Liu; Jeffrey Patrick; Joseph M Scavone; Jeremias Antinew
Journal:  Epilepsia Open       Date:  2021-05-16

10.  Agitation and Sugar Craving Related to Epilepsy Seizure.

Authors:  Rania Adel Hameed; Mohammad Reza F Aghdam
Journal:  Case Rep Psychiatry       Date:  2021-05-03
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