| Literature DB >> 28114859 |
David Martínez-Jiménez1,2,3,4,5, Bridget Garner1,2,3,4,5, Sheryl Coutermarsh-Ott1,2,3,4,5, Caitlin Burrell1,2,3,4,5, Sabrina Clark1,2,3,4,5, Mary Nabity1,2,3,4,5, Josué Díaz-Delgado1,2,3,4,5, Aline Rodrigues-Hoffmann1,2,3,4,5, Karen Zaks1,2,3,4,5, Laila Proença1,2,3,4,5, Stephen Divers1,2,3,4,5, Corey Saba1,2,3,4,5, Paola Cazzini1,2,3,4,5.
Abstract
Neoplasia is usually encountered in the African pygmy hedgehog at a mean age of 3.5 y, and malignancy is common. Myelogenous leukemias are rarely reported in hedgehogs. We describe 3 cases of eosinophilic leukemia in adult, middle-aged (mean age: 2.3 y) hedgehogs, for which prognosis appears grave. In 1 case, attempted treatment was unsuccessful, and in all 3 cases, the disease course was rapid and all died soon after diagnosis. Blood smear evaluation, along with complete blood count, was critical in making the diagnosis in all cases. Luna stain was validated and used to better visualize eosinophils in cytologic and histologic sections. Electron microscopy confirmed the presence of specific granules in hedgehog eosinophils.Entities:
Keywords: African pygmy hedgehog; Atelerix albiventris; Luna stain; eosinophilic leukemia; myeloproliferative disease; neoplasia
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Year: 2017 PMID： 28114859 DOI： 10.1177/1040638716687603
Source DB: PubMed Journal: J Vet Diagn Invest ISSN： 1040-6387 Impact factor: 1.279