Filter Design with Adaptation to Time-Delay Parameters for Genetic Regulatory Networks.

In existing works, the filters designed for delayed genetic regulatory networks contain time delay. If the time delay is unknown, the filters do not work in practical applications. In order to overcome the shortcoming in such existing works, this paper investigates the filter design problem of genetic regulatory networks with unknown constant time delay, and a novel adaptive filter is introduced, which can estimate online not only unknown network parameters but also the unknown time delay. By the Lyapunove approach, it is shown that the estimating errors asymptotically converge to the origin. Finally, simulation results are presented to illustrate the effectiveness of the proposed new design method.