Chiara S Haller1,2, Cecile Delhumeau3, Michael De Pretto3, Rahel Schumacher4, Laura Pielmaier5, Marie My Lien Rebetez6, Guy Haller3,7, Bernhard Walder3. 1. a Department of Psychology , Harvard University, Cambridge , Boston , MA , USA. 2. b Division of Public Psychiatry , Massachusetts Mental Health Center , Boston , MA , USA. 3. c Division of Anaesthesiology , University Hospitals of Geneva (HUG) , Geneva , Switzerland. 4. d Division of Cognitive and Restorative Neurology, Department of Neurology , Inselspital, Bern University Hospital, and University of Bern , Bern , Switzerland. 5. e Psychiatric Service Aargau , Windisch , Switzerland. 6. f Department of Clinical Psychology , University of Geneva , Geneva , Switzerland. 7. g Division of Clinical Epidemiology , University Hospitals of Geneva (HUG) , Geneva , Switzerland.
Abstract
OBJECTIVE: The objective was to investigate disability and health-related quality-of-life (HRQoL) 3, 6 and 12 months after traumatic brain injury (TBI) in non-geriatric (≤ 65 years) and geriatric patients (> 65 years). METHODS: Patients ≥ 16 years who sustained a severe TBI (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. Outcome measures were Glasgow Outcome Scale Extended (GOSE; disability), SF-12 (HRQoL). Mixed linear model analyses were performed. RESULTS: Three hundred and fifty-one patients (median age = 50 years; interquartile range (IQR) = 27-67) were included; 73.2% were male and 27.6% were geriatric patients. Median GOSE at 3, 6 and 12 months was 5 (IQR = 3-7), 6 (IQR = 4-8) and 7 (IQR = 5-8); this increase (slopetime = 0.22, p < 0.0001) was age dependent (slopeage*time = -0.06, p = 0.003). Median SF-12 physical component scale score at 3, 6 and 12 months was 42.1 (IQR = 33.6-50.7), 46.6 (IQR = 37.4-53.9) and 50.4 (IQR = 39.2-55.1); this increase (slopetime = 1.52, p < 0.0001) was not age dependent (slopeage*time = -0.30, p = 0.083). SF-12 mental component scale scores were unchanged. CONCLUSIONS: Disability decreased and HRQoL improved after TBI between 3-12 months. In geriatric patients this improvement was relevant for HRQoL only.
OBJECTIVE: The objective was to investigate disability and health-related quality-of-life (HRQoL) 3, 6 and 12 months after traumatic brain injury (TBI) in non-geriatric (≤ 65 years) and geriatric patients (> 65 years). METHODS:Patients ≥ 16 years who sustained a severe TBI (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. Outcome measures were Glasgow Outcome Scale Extended (GOSE; disability), SF-12 (HRQoL). Mixed linear model analyses were performed. RESULTS: Three hundred and fifty-one patients (median age = 50 years; interquartile range (IQR) = 27-67) were included; 73.2% were male and 27.6% were geriatric patients. Median GOSE at 3, 6 and 12 months was 5 (IQR = 3-7), 6 (IQR = 4-8) and 7 (IQR = 5-8); this increase (slopetime = 0.22, p < 0.0001) was age dependent (slopeage*time = -0.06, p = 0.003). Median SF-12 physical component scale score at 3, 6 and 12 months was 42.1 (IQR = 33.6-50.7), 46.6 (IQR = 37.4-53.9) and 50.4 (IQR = 39.2-55.1); this increase (slopetime = 1.52, p < 0.0001) was not age dependent (slopeage*time = -0.30, p = 0.083). SF-12 mental component scale scores were unchanged. CONCLUSIONS: Disability decreased and HRQoL improved after TBI between 3-12 months. In geriatric patients this improvement was relevant for HRQoL only.
Entities:
Keywords:
Head injury; elderly; functional outcome; health-related quality-of-life; recovery
Authors: Sarah E P Munce; Susan Jaglal; Monika Kastner; Michelle L A Nelson; Nancy M Salbach; John Shepherd; Shane N Sweet; Ruth Wilcock; Carla Thoms; Mark T Bayley Journal: BMJ Open Date: 2019-03-23 Impact factor: 2.692
Authors: Eva Visser; Brenda Leontine Den Oudsten; Taco Gosens; Paul Lodder; Jolanda De Vries Journal: Qual Life Res Date: 2021-01-14 Impact factor: 4.147
Authors: Cindy Hunt; Shatabdy Zahid; Naomi Ennis; Alicja Michalak; Cheryl Masanic; Chantal Vaidyanath; Shree Bhalerao; Michael D Cusimano; Andrew Baker Journal: Qual Life Res Date: 2019-09-14 Impact factor: 4.147