Literature DB >> 28112845

Amplified Photodegradation of Cell-Laden Hydrogels via an Addition-Fragmentation Chain Transfer Reaction.

Tobin E Brown1, Ian A Marozas1, Kristi S Anseth1,2.   

Abstract

Hydrogels crosslinked by allyl-sulfide-containing molecules are presented. By exposure to light in the presence of a photoinitiator and a free monofunctional thiol, photodegradation is achieved. Both the gelation and degradation are cytocompatible and allow for cell encapsulation and subsequent release. The photodegradation kinetics and depths attainable are superior to those of traditional cell-laden photodegradable hydrogels.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  AFCT; adaptable networks; hydrogels; photodegradation; thiol-ene

Year:  2017        PMID: 28112845      PMCID: PMC5489340          DOI: 10.1002/adma.201605001

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  41 in total

1.  A highly selective FRET-based fluorescent probe for detection of cysteine and homocysteine.

Authors:  Hoi-Yan Shiu; Hiu-Chi Chong; Yun-Chung Leung; Man-Kin Wong; Chi-Ming Che
Journal:  Chemistry       Date:  2010-03-15       Impact factor: 5.236

2.  Photo-crosslinkable PEG-based microribbons for forming 3D macroporous scaffolds with decoupled niche properties.

Authors:  Li-Hsin Han; Xinming Tong; Fan Yang
Journal:  Adv Mater       Date:  2013-12-17       Impact factor: 30.849

3.  In situ cell manipulation through enzymatic hydrogel photopatterning.

Authors:  Katarzyna A Mosiewicz; Laura Kolb; André J van der Vlies; Mikaël M Martino; Philipp S Lienemann; Jeffrey A Hubbell; Martin Ehrbar; Matthias P Lutolf
Journal:  Nat Mater       Date:  2013-10-13       Impact factor: 43.841

4.  Dynamic phototuning of 3D hydrogel stiffness.

Authors:  Ryan S Stowers; Shane C Allen; Laura J Suggs
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-02       Impact factor: 11.205

5.  Rational design of network properties in guest-host assembled and shear-thinning hyaluronic acid hydrogels.

Authors:  Christopher B Rodell; Adam L Kaminski; Jason A Burdick
Journal:  Biomacromolecules       Date:  2013-10-14       Impact factor: 6.988

6.  Photo-selective delivery of model therapeutics from hydrogels.

Authors:  Donald R Griffin; Andrea M Kasko
Journal:  ACS Macro Lett       Date:  2012-11-20       Impact factor: 6.903

7.  Photoreversible patterning of biomolecules within click-based hydrogels.

Authors:  Cole A DeForest; Kristi S Anseth
Journal:  Angew Chem Int Ed Engl       Date:  2011-12-08       Impact factor: 15.336

8.  Photo-click living strategy for controlled, reversible exchange of biochemical ligands.

Authors:  Navakanth R Gandavarapu; Malar A Azagarsamy; Kristi S Anseth
Journal:  Adv Mater       Date:  2014-02-12       Impact factor: 30.849

9.  Modeling Controlled Photodegradation in Optically Thick Hydrogels.

Authors:  Mark W Tibbitt; April M Kloxin; Kristi S Anseth
Journal:  J Polym Sci A Polym Chem       Date:  2013-05-01       Impact factor: 2.702

10.  Thiol-ene photopolymerizations provide a facile method to encapsulate proteins and maintain their bioactivity.

Authors:  Joshua D McCall; Kristi S Anseth
Journal:  Biomacromolecules       Date:  2012-07-20       Impact factor: 6.988

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  24 in total

1.  PEG-Anthracene Hydrogels as an On-Demand Stiffening Matrix To Study Mechanobiology.

Authors:  Kemal Arda Günay; Tova L Ceccato; Jason S Silver; Kendra L Bannister; Olivia J Bednarski; Leslie A Leinwand; Kristi S Anseth
Journal:  Angew Chem Int Ed Engl       Date:  2019-06-11       Impact factor: 15.336

2.  Ruthenium-Crosslinked Hydrogels with Rapid, Visible-Light Degradation.

Authors:  Teresa L Rapp; Christopher B Highley; Brian C Manor; Jason A Burdick; Ivan J Dmochowski
Journal:  Chemistry       Date:  2018-01-10       Impact factor: 5.236

3.  Flow Behavior Prior to Crosslinking: The Need for Precursor Rheology for Placement of Hydrogels in Medical Applications and for 3D Bioprinting.

Authors:  Jakob M Townsend; Emily C Beck; Stevin H Gehrke; Cory J Berkland; Michael S Detamore
Journal:  Prog Polym Sci       Date:  2019-01-17       Impact factor: 29.190

4.  Chemical Approaches to Dynamically Modulate the Properties of Synthetic Matrices.

Authors:  Paige J LeValley; April M Kloxin
Journal:  ACS Macro Lett       Date:  2018-12-22       Impact factor: 6.903

Review 5.  Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise.

Authors:  H-H Greco Song; Rowza T Rumma; C Keith Ozaki; Elazer R Edelman; Christopher S Chen
Journal:  Cell Stem Cell       Date:  2018-03-01       Impact factor: 24.633

6.  4D Printing of Extrudable and Degradable Poly(Ethylene Glycol) Microgel Scaffolds for Multidimensional Cell Culture.

Authors:  Connor E Miksch; Nathaniel P Skillin; Bruce E Kirkpatrick; Grace K Hach; Varsha V Rao; Timothy J White; Kristi S Anseth
Journal:  Small       Date:  2022-06-22       Impact factor: 15.153

7.  Relaxation of Extracellular Matrix Forces Directs Crypt Formation and Architecture in Intestinal Organoids.

Authors:  Ella A Hushka; F Max Yavitt; Tobin E Brown; Peter J Dempsey; Kristi S Anseth
Journal:  Adv Healthc Mater       Date:  2020-01-20       Impact factor: 9.933

8.  The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging.

Authors:  F Max Yavitt; Tobin E Brown; Ella A Hushka; Monica E Brown; Nikolche Gjorevski; Peter J Dempsey; Matthias P Lutolf; Kristi S Anseth
Journal:  Adv Mater       Date:  2020-06-17       Impact factor: 30.849

Review 9.  Spatiotemporal hydrogel biomaterials for regenerative medicine.

Authors:  Tobin E Brown; Kristi S Anseth
Journal:  Chem Soc Rev       Date:  2017-10-30       Impact factor: 54.564

Review 10.  Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels.

Authors:  Matthew R Arkenberg; Han D Nguyen; Chien-Chi Lin
Journal:  J Mater Chem B       Date:  2020-07-21       Impact factor: 6.331

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