| Literature DB >> 28111101 |
Giacomo Traini1, Giuseppe Battistoni2, Angela Bollella3, Francesco Collamati1, Erika De Lucia4, Riccardo Faccini1, Fernando Ferroni1, Paola Maria Frallicciardi5, Carlo Mancini-Terracciano1, Michela Marafini6, Ilaria Mattei2, Federico Miraglia3, Silvia Muraro2, Riccardo Paramatti1, Luca Piersanti4, Davide Pinci7, Antoni Rucinski6, Andrea Russomando1, Alessio Sarti6, Adalberto Sciubba8, Martina Senzacqua9, Elena Solfaroli-Camillocci1, Marco Toppi4, Cecilia Voena10, Vincenzo Patera8.
Abstract
Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition to the tumor and surrounding tissues. The design of a new tracking device for beam range real-time monitoring in pencil beam carbon ion therapy is presented. The proposed device tracks secondary charged particles produced by beam interactions in the patient tissue and exploits the correlation of the charged particle emission profile with the spatial dose deposition and the Bragg peak position. The detector, currently under construction, uses the information provided by 12 layers of scintillating fibers followed by a plastic scintillator and a pixelated Lutetium Fine Silicate (LFS) crystal calorimeter. An algorithm to account and correct for emission profile distortion due to charged secondaries absorption inside the patient tissue is also proposed. Finally detector reconstruction efficiency for charged particle emission profile is evaluated using a Monte Carlo simulation considering a quasi-realistic case of a non-homogenous phantom.Entities:
Keywords: Hadron therapy; Particle detection; Real time monitoring
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Year: 2017 PMID: 28111101 DOI: 10.1016/j.ejmp.2017.01.004
Source DB: PubMed Journal: Phys Med ISSN: 1120-1797 Impact factor: 2.685