| Literature DB >> 28110711 |
Caterina Missero1, Dario Antonini2.
Abstract
The p63 gene is often overexpressed in squamous cell carcinomas; however, how its overexpression contributes to tumor formation and expansion is still incompletely understood. Devos et al. report the development of a versatile mouse model demonstrating that p63 facilitates squamous cell carcinoma formation in skin and providing an excellent tool to dissect the relevance of its downstream signaling pathways in tumorigenesis.Entities:
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Year: 2017 PMID： 28110711 DOI： 10.1016/j.jid.2016.10.032
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551