Literature DB >> 28109477

Clinical outcomes following cochlear implantation in children with inner ear anomalies.

Amal Isaiah1, Daniel Lee2, Felicity Lenes-Voit1, Melissa Sweeney3, Walter Kutz1, Brandon Isaacson1, Peter Roland1, Kenneth H Lee4.   

Abstract

OBJECTIVE: A significant proportion of children with congenital hearing loss who are candidates for cochlear implants (CIs) may have inner ear malformations (IEMs). Surgical and speech outcomes following CI in these children have not been widely reported.
METHODS: The charts of children who were evaluated for a CI between 1/1/1986 and 12/31/2014 at a university-based tertiary level pediatric cochlear implant center were reviewed. Principal inclusion criteria included (i) age 1-18 years, (ii) history of bilateral severe to profound sensorineural hearing loss, and (iii) limited benefit from binaural amplification. Exclusion criteria included (i) underlying diagnosis of neurodevelopmental disorder and (ii) lack of follow up for speech assessment if a CI was performed. The following outcome measures were reviewed: (i) imaging findings with magnetic resonance imaging or high resolution computed tomography, (ii) intraoperative complications, and (iii) speech perception categorized as the ability to perceive closed set, open set, or none.
RESULTS: The prevalence of IEMs was 27% (102 of 381), of which 79% were bilateral. Cochlear dysplasia accounted for 30% (40 of 136) of the anomalies. Seventy-eight of the 102 patients received a CI (78%). Surgery was noted to be challenging in 24% (19 of 78), with a perilymphatic gusher being the most common intraoperative finding. Cochlear dysplasia, vestibular dysplasia and cochlear nerve hypoplasia were associated with poor speech perception (open OR closed set speech recognition scores, 0-23%), although the outcomes in children with enlarged vestibular aqueduct were similar to those of children with normal inner ear anatomy (65%).
CONCLUSIONS: Cochlear implantation is safe in children with IEMs. However, the speech perception outcomes are notably below those of patients with normal anatomy, with the exception of when an enlarged vestibular aqueduct is present.
Copyright © 2016. Published by Elsevier B.V.

Entities:  

Keywords:  Cochlear implants; Hearing restoration; Inner ear malformations; Speech recognition

Mesh:

Year:  2016        PMID: 28109477     DOI: 10.1016/j.ijporl.2016.12.001

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  7 in total

1.  Spatial and temporal inhibition of FGFR2b ligands reveals continuous requirements and novel targets in mouse inner ear morphogenesis.

Authors:  Lisa D Urness; Xiaofen Wang; Huy Doan; Nathan Shumway; C Albert Noyes; Edgar Gutierrez-Magana; Ree Lu; Suzanne L Mansour
Journal:  Development       Date:  2018-12-18       Impact factor: 6.868

Review 2.  Cochlear implantation in adults and pediatrics with enlarged vestibular aqueduct: a systematic review on the surgical findings and patients' performance.

Authors:  Asma Alahmadi; Yassin Abdelsamad; Marzouqi Salamah; Saad Alenzi; Khalid M Badr; Saeed Alghamdi; Abdulrahman Alsanosi
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-06-30       Impact factor: 2.503

3.  New SMS Classification of Cochleovestibular Anomalies: Our Experience with 25 Cases of Type I Anomaly.

Authors:  Mohnish Grover; Shivam Sharma; Sunil Samdani; Gaurav Gupta; Chappati Preetam; Kriti Gera; Jairaj Kumar Vaishnav; Mahendra Kumar Hada
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2021-02-20

4.  Internal auditory canal volume in normal and malformed inner ears.

Authors:  David Bächinger; Tabita M Breitsprecher; Alexander Pscheidl; Anandhan Dhanasingh; Robert Mlynski; Stefan Dazert; Sönke Langner; Nora M Weiss
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-10-09       Impact factor: 3.236

5.  Electrically evoked auditory brainstem responses in deaf patients with Mondini malformation during cochlear implantation.

Authors:  Han-Yu Zhu; Li Chen; Xiao-Yan Hou; Zheng-Quan Tang; Jia-Qiang Sun; Jing-Wu Sun; Xiao-Tao Guo
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-03-05       Impact factor: 3.236

6.  Systematic review of cochlear implantation in patients with inner ear malformations.

Authors:  Sunny Shah; Rameen Walters; Jake Langlie; Camron Davies; Ariel Finberg; Maria-Pia Tuset; Dario Ebode; Rahul Mittal; Adrien A Eshraghi
Journal:  PLoS One       Date:  2022-10-21       Impact factor: 3.752

7.  Correlation of cochlear aperture stenosis with cochlear nerve deficiency in congenital unilateral hearing loss and prognostic relevance for cochlear implantation.

Authors:  Eva Orzan; Giulia Pizzamiglio; Massimo Gregori; Raffaella Marchi; Lucio Torelli; Enrico Muzzi
Journal:  Sci Rep       Date:  2021-02-08       Impact factor: 4.379

  7 in total

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