Katherine Rieke1, Kendra K Schmid2, William Lydiatt3, Julia Houfek4, Eugene Boilesen5, Shinobu Watanabe-Galloway6. 1. Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States. 2. Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States. 3. Department of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center and Nebraska Methodist Hospital, Omaha, NE, United States. 4. College of Nursing, University of Nebraska Medical Center, Omaha, NE, United States. 5. Center for Collaboration on Research Design and Analysis, University of Nebraska Medical Center, Omaha, NE, United States. 6. Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States. Electronic address: swatanabe@unmc.edu.
Abstract
OBJECTIVE: Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. MATERIALS AND METHODS: This study used SEER-Medicare data from 2002-2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. RESULTS: Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR=1.49; 95% CI=1.27, 1.76 and HR=1.38; 95% CI=1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR=1.55; 95% CI=1.36, 1.76 and HR=1.40; 95% CI=1.21, 1.62, respectively). CONCLUSIONS: The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.
OBJECTIVE: Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. MATERIALS AND METHODS: This study used SEER-Medicare data from 2002-2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. RESULTS: Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR=1.49; 95% CI=1.27, 1.76 and HR=1.38; 95% CI=1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR=1.55; 95% CI=1.36, 1.76 and HR=1.40; 95% CI=1.21, 1.62, respectively). CONCLUSIONS: The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.
Authors: David W Kissane; Snehal G Patel; Raymond E Baser; Rachel Bell; Maria Farberov; Jamie S Ostroff; Yuelin Li; Bhuvanesh Singh; Dennis H Kraus; Jatin P Shah Journal: Head Neck Date: 2012-02-24 Impact factor: 3.147
Authors: Mary Ellen Haisfield-Wolfe; Deborah B McGuire; Karen Soeken; Jeanne Geiger-Brown; Bruce R De Forge Journal: Oncol Nurs Forum Date: 2009-05 Impact factor: 2.172
Authors: Andrea Vodermaier; Wolfgang Linden; Katerina Rnic; Sandra N Young; Alvina Ng; Nina Ditsch; Robert Olson Journal: Breast Cancer Res Treat Date: 2013-12-13 Impact factor: 4.872
Authors: Mark A Ellis; Katherine R Sterba; Terry A Day; Courtney H Marsh; Stacy Maurer; Elizabeth G Hill; Evan M Graboyes Journal: Otolaryngol Head Neck Surg Date: 2019-04-09 Impact factor: 3.497
Authors: V C Sandulache; Y L Lei; L E Heasley; M Chang; C I Amos; E M Sturgis; E Graboyes; E Y Chiao; N Rogus-Pulia; J Lewis; A Madabhushi; M J Frederick; A Sabichi; M Ittmann; W G Yarbrough; C H Chung; R Ferrarotto; Weiyuan Mai; H D Skinner; U Duvvuri; P Gerngross; A G Sikora Journal: Oral Oncol Date: 2019-10-22 Impact factor: 5.337
Authors: I Ghanem; B Castelo; P Jimenez-Fonseca; A Carmona-Bayonas; O Higuera; C Beato; T García; R Hernández; C Calderon Journal: Clin Transl Oncol Date: 2019-05-10 Impact factor: 3.405
Authors: Lauren A Zimmaro; Sandra E Sephton; Chelsea J Siwik; Kala M Phillips; Whitney N Rebholz; Helena C Kraemer; Janine Giese-Davis; Liz Wilson; Jeffrey M Bumpous; Elizabeth D Cash Journal: Cancer Date: 2018-01-22 Impact factor: 6.860
Authors: William C Chen; Lauren Boreta; Steve E Braunstein; Michael W Rabow; Lawrence E Kaplan; Jessica D Tenenbaum; Olivier Morin; Catherine C Park; Julian C Hong Journal: Cancer Date: 2021-09-22 Impact factor: 6.860
Authors: Laura B Oswald; Brandy Arredondo; Carley Geiss; Taylor F D Vigoureux; Aasha I Hoogland; Christine H Chung; Jameel Muzaffar; Krupal B Patel; Brian D Gonzalez; Heather S L Jim; Kedar Kirtane Journal: Psychooncology Date: 2022-07-03 Impact factor: 3.955