| Literature DB >> 28108863 |
Tom Rosenström1, Eivind Ystrom2,3,4, Fartein Ask Torvik2, Nikolai Olavi Czajkowski2,3, Nathan A Gillespie5, Steven H Aggen5, Robert F Krueger6, Kenneth S Kendler5,7,8, Ted Reichborn-Kjennerud2,9.
Abstract
Results from previous studies on DSM-IV and DSM-5 Antisocial Personality Disorder (ASPD) have suggested that the construct is etiologically multidimensional. To our knowledge, however, the structure of genetic and environmental influences in ASPD has not been examined using an appropriate range of biometric models and diagnostic interviews. The 7 ASPD criteria (section A) were assessed in a population-based sample of 2794 Norwegian twins by a structured interview for DSM-IV personality disorders. Exploratory analyses were conducted at the phenotypic level. Multivariate biometric models, including both independent and common pathways, were compared. A single phenotypic factor was found, and the best-fitting biometric model was a single-factor common pathway model, with common-factor heritability of 51% (95% CI 40-67%). In other words, both genetic and environmental correlations between the ASPD criteria could be accounted for by a single common latent variable. The findings support the validity of ASPD as a unidimensional diagnostic construct.Entities:
Keywords: Common pathway; Diagnostics; Multivariate biometric model; Psychometrics; Unidimensionality
Mesh：
Year: 2017 PMID： 28108863 PMCID： PMC5404958 DOI： 10.1007/s10519-016-9833-z
Source DB: PubMed Journal: Behav Genet ISSN： 0001-8244 Impact factor: 2.805