Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation.

Literature DB >> 28108485

TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation.

Abstract

Soon after the discovery of transforming growth factor-β (TGF-β), seminal work in vertebrate and invertebrate models revealed the TGF-β family to be central regulators of tissue morphogenesis. Members of the TGF-β family direct some of the earliest cell-fate decisions in animal development, coordinate complex organogenesis, and contribute to tissue homeostasis in the adult. Here, we focus on the role of the TGF-β family in mammalian stem-cell biology and discuss its wide and varied activities both in the regulation of pluripotency and in cell-fate commitment.

Entities: Gene Species

Mesh：

Substances：

Year: 2017 PMID： 28108485 PMCID： PMC5495062 DOI： 10.1101/cshperspect.a022186

Source DB: PubMed Journal: Cold Spring Harb Perspect Biol ISSN： 1943-0264 Impact factor: 10.005

314 in total

1. Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.

Authors: C Sirard; S Kim; C Mirtsos; P Tadich; P A Hoodless; A Itié; R Maxson; J L Wrana; T W Mak
Journal: J Biol Chem Date: 2000-01-21 Impact factor: 5.157

2. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells.

Authors: S H Cheshier; S J Morrison; X Liao; I L Weissman
Journal: Proc Natl Acad Sci U S A Date: 1999-03-16 Impact factor: 11.205

3. Bmp4 is required for the generation of primordial germ cells in the mouse embryo.

Authors: K A Lawson; N R Dunn; B A Roelen; L M Zeinstra; A M Davis; C V Wright; J P Korving; B L Hogan
Journal: Genes Dev Date: 1999-02-15 Impact factor: 11.361

4. Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction.

Authors: M B Datto; J P Frederick; L Pan; A J Borton; Y Zhuang; X F Wang
Journal: Mol Cell Biol Date: 1999-04 Impact factor: 4.272

5. A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.

Authors: E Weisberg; G E Winnier; X Chen; C L Farnsworth; B L Hogan; M Whitman
Journal: Mech Dev Date: 1998-12 Impact factor: 1.882

6. Multilineage potential of adult human mesenchymal stem cells.

Authors: M F Pittenger; A M Mackay; S C Beck; R K Jaiswal; R Douglas; J D Mosca; M A Moorman; D W Simonetti; S Craig; D R Marshak
Journal: Science Date: 1999-04-02 Impact factor: 47.728

7. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

Authors: J S Munger; X Huang; H Kawakatsu; M J Griffiths; S L Dalton; J Wu; J F Pittet; N Kaminski; C Garat; M A Matthay; D B Rifkin; D Sheppard
Journal: Cell Date: 1999-02-05 Impact factor: 41.582

8. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.

Authors: S P Oh; T Seki; K A Goss; T Imamura; Y Yi; P K Donahoe; L Li; K Miyazono; P ten Dijke; S Kim; E Li
Journal: Proc Natl Acad Sci U S A Date: 2000-03-14 Impact factor: 11.205

9. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells.

Authors: M Bhatia; D Bonnet; D Wu; B Murdoch; J Wrana; L Gallacher; J E Dick
Journal: J Exp Med Date: 1999-04-05 Impact factor: 14.307

10. Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling.

Authors: H Harada; P Kettunen; H S Jung; T Mustonen; Y A Wang; I Thesleff
Journal: J Cell Biol Date: 1999-10-04 Impact factor: 10.539

41 in total

Review 1. Specificity, versatility, and control of TGF-β family signaling.

Authors: Rik Derynck; Erine H Budi
Journal: Sci Signal Date: 2019-02-26 Impact factor: 8.192

2. Molecular network of miR-1343 regulates the pluripotency of porcine pluripotent stem cells via repressing OTX2 expression.

Authors: Youlong Xie; Hongxia Cao; Zhiyi Zhang; Shiqiang Zhang; Huayan Wang
Journal: RNA Biol Date: 2018-12-27 Impact factor: 4.652

3. Transforming growth factor-β (TGF-β)-induced up-regulation of TGF-β receptors at the cell surface amplifies the TGF-β response.

Authors: Dana Duan; Rik Derynck
Journal: J Biol Chem Date: 2019-04-04 Impact factor: 5.157

4. Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes.

Authors: Alicia V Zamudio; Alessandra Dall'Agnese; Jonathan E Henninger; John C Manteiga; Lena K Afeyan; Nancy M Hannett; Eliot L Coffey; Charles H Li; Ozgur Oksuz; Benjamin R Sabari; Ann Boija; Isaac A Klein; Susana W Hawken; Jan-Hendrik Spille; Tim-Michael Decker; Ibrahim I Cisse; Brian J Abraham; Tong I Lee; Dylan J Taatjes; Jurian Schuijers; Richard A Young
Journal: Mol Cell Date: 2019-09-25 Impact factor: 17.970

Review 5. Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family.

Authors: Sun Kyung Kim; Morkos A Henen; Andrew P Hinck
Journal: Exp Biol Med (Maywood) Date: 2019-10-10

6. Development of luspatercept to treat ineffective erythropoiesis.

Authors: Anne Sophie Kubasch; Pierre Fenaux; Uwe Platzbecker
Journal: Blood Adv Date: 2021-03-09

7. Structural Adaptation in Its Orphan Domain Engenders Betaglycan with an Alternate Mode of Growth Factor Binding Relative to Endoglin.

Authors: Sun Kyung Kim; Matthew J Whitley; Troy C Krzysiak; Cynthia S Hinck; Alexander B Taylor; Christian Zwieb; Chang-Hyeock Byeon; Xiaohong Zhou; Valentín Mendoza; Fernando López-Casillas; William Furey; Andrew P Hinck
Journal: Structure Date: 2019-07-18 Impact factor: 5.006

Review 8. Biological basis for efficacy of activin receptor ligand traps in myelodysplastic syndromes.

Authors: Amit Verma; Rajasekhar Nvs Suragani; Srinivas Aluri; Nishi Shah; Tushar D Bhagat; Mark J Alexander; Rami Komrokji; Ravi Kumar
Journal: J Clin Invest Date: 2020-02-03 Impact factor: 14.808

Review 9. TGFβ-Directed Therapeutics: 2020.

Authors: Beverly A Teicher
Journal: Pharmacol Ther Date: 2020-08-21 Impact factor: 12.310

Review 10. Low complexity domains, condensates, and stem cell pluripotency.

Authors: Munender Vodnala; Eun-Bee Choi; Yick W Fong
Journal: World J Stem Cells Date: 2021-05-26 Impact factor: 5.326