Literature DB >> 28107867

An update on the 2014 Ebola outbreak in Western Africa.

Haaris A Shiwani1, Rebabonye B Pharithi2, Barkat Khan2, Christian Binoun-A Egom3, Peter Kruzliak4, Vincent Maher2, Emmanuel Eroume-A Egom5.   

Abstract

The recent Ebola outbreak in Western Africa was the most devastating outbreak witnessed in recent times. There have been remarkable local and international efforts to control the crisis. Ebola Virus Disease is the focus of immense research activity. The progression of events in the region has been evolving swiftly and it is of paramount importance to the medical community to be acquainted with the situation. Over 28000 people were inflicted with the condition, over 11000 have died. Novel data has emerged regarding modes of transmission, providing rationale for recent flare-ups. Similarly, studies on survivors are elucidating the later stages of the disease recovery process. Novel techniques for diagnosis are also discussed. Finally, the current research regarding treatment and vaccine development is reviewed, particularly the implementation of rVSV-ZEBOV vaccination programs.
Copyright © 2017 Hainan Medical University. Production and hosting by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  EBOV; Ebola virus disease; Ebola virus vaccination; Western Africa

Year:  2016        PMID: 28107867     DOI: 10.1016/j.apjtm.2016.12.008

Source DB:  PubMed          Journal:  Asian Pac J Trop Med        ISSN: 1995-7645            Impact factor:   1.226


  5 in total

1.  Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial.

Authors:  May S ElSherif; Catherine Brown; Donna MacKinnon-Cameron; Li Li; Trina Racine; Judie Alimonti; Thomas L Rudge; Carol Sabourin; Peter Silvera; Jay W Hooper; Steven A Kwilas; Nicole Kilgore; Christopher Badorrek; W Jay Ramsey; D Gray Heppner; Tracy Kemp; Thomas P Monath; Teresa Nowak; Shelly A McNeil; Joanne M Langley; Scott A Halperin
Journal:  CMAJ       Date:  2017-06-19       Impact factor: 8.262

2.  Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents.

Authors:  Xin Zhang; Qiang Liu; Qianqian Li; Yinghong Li; Zhandong Liu; Hongbin Deng; Sheng Tang; Yanxiang Wang; Youchun Wang; Danqing Song
Journal:  Acta Pharm Sin B       Date:  2018-02-21       Impact factor: 11.413

3.  The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus.

Authors:  Luke D Jasenosky; Cristhian Cadena; Chad E Mire; Viktoriya Borisevich; Viraga Haridas; Shahin Ranjbar; Aya Nambu; Sina Bavari; Veronica Soloveva; Supriya Sadukhan; Gail H Cassell; Thomas W Geisbert; Sun Hur; Anne E Goldfeld
Journal:  iScience       Date:  2019-08-08

4.  Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs.

Authors:  Samira Locher; Marc Schweneker; Jürgen Hausmann; Gert Zimmer
Journal:  J Gen Virol       Date:  2018-06-05       Impact factor: 3.891

5.  Exposure to Ebola Virus and Risk for Infection with Malaria Parasites, Rural Gabon.

Authors:  Jessica L Abbate; Pierre Becquart; Eric Leroy; Vanessa O Ezenwa; Benjamin Roche
Journal:  Emerg Infect Dis       Date:  2020-02-17       Impact factor: 6.883

  5 in total

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