PURPOSE OF REVIEW: To summarize the recent evidence on the treatment of abdominal sepsis with a specific emphasis on the surgical treatment. RECENT FINDINGS: A multitude of surgical approaches towards abdominal sepsis are practised. Recent evidence shows that immediate closure of the abdomen has a better outcome. A short course of antibiotics has a similar effect as a long course of antibiotics in patients with intra-abdominal infection without severe sepsis. SUMMARY: Management of abdominal sepsis requires a multidisciplinary approach. Closing the abdomen permanently after source control and only reopening it in case of deterioration of the patient without other (percutaneous) options is the preferred strategy. There is no convincing evidence that damage control surgery is beneficial in patients with abdominal sepsis. If primary closure of the abdomen is impossible because of excessive visceral edema, delayed closure using negative pressure therapy with continuous mesh-mediated fascial traction shows the best results.
PURPOSE OF REVIEW: To summarize the recent evidence on the treatment of abdominal sepsis with a specific emphasis on the surgical treatment. RECENT FINDINGS: A multitude of surgical approaches towards abdominal sepsis are practised. Recent evidence shows that immediate closure of the abdomen has a better outcome. A short course of antibiotics has a similar effect as a long course of antibiotics in patients with intra-abdominal infection without severe sepsis. SUMMARY: Management of abdominal sepsis requires a multidisciplinary approach. Closing the abdomen permanently after source control and only reopening it in case of deterioration of the patient without other (percutaneous) options is the preferred strategy. There is no convincing evidence that damage control surgery is beneficial in patients with abdominal sepsis. If primary closure of the abdomen is impossible because of excessive visceral edema, delayed closure using negative pressure therapy with continuous mesh-mediated fascial traction shows the best results.
Authors: Christen E Salyer; Christian B Bergmann; Richard S Hotchkiss; Peter A Crisologo; Charles C Caldwell Journal: J Surg Res Date: 2022-02-05 Impact factor: 2.417
Authors: Andrew W Kirkpatrick; Federico Coccolini; Luca Ansaloni; Derek J Roberts; Matti Tolonen; Jessica L McKee; Ari Leppaniemi; Peter Faris; Christopher J Doig; Fausto Catena; Timothy Fabian; Craig N Jenne; Osvaldo Chiara; Paul Kubes; Braden Manns; Yoram Kluger; Gustavo P Fraga; Bruno M Pereira; Jose J Diaz; Michael Sugrue; Ernest E Moore; Jianan Ren; Chad G Ball; Raul Coimbra; Zsolt J Balogh; Fikri M Abu-Zidan; Elijah Dixon; Walter Biffl; Anthony MacLean; Ian Ball; John Drover; Paul B McBeth; Juan G Posadas-Calleja; Neil G Parry; Salomone Di Saverio; Carlos A Ordonez; Jimmy Xiao; Massimo Sartelli Journal: World J Emerg Surg Date: 2018-06-22 Impact factor: 5.469
Authors: Christopher J Doig; Stacey A Page; Jessica L McKee; Ernest E Moore; Fikri M Abu-Zidan; Rosemary Carroll; John C Marshall; Peter D Faris; Matti Tolonen; Fausto Catena; Federico Cocolini; Massimo Sartelli; Luca Ansaloni; Sam F Minor; Bruno M Peirera; Jose J Diaz; Andrew W Kirkpatrick Journal: World J Emerg Surg Date: 2019-08-05 Impact factor: 5.469