Literature DB >> 28104987

Estimation of quality of life in Cypriot patients with inflammatory bowel disease.

Maria Tsoukka1, Eleni Jelastopulu1, Giagkos Lavranos1, George Charalambous1.   

Abstract

AIM: To investigate the health-related quality of life (HRQoL) of patients suffering with idiopathic inflammatory bowel disease (IBD).
METHODS: The Greek validated version of the Short Inflammatory Bowel Disease Questionnaire was used for evaluating the quality of life of IBD patients. The questionnaire was distributed to 100 consecutive patients suffering from IBD and presenting for a clinic appointment at the endoscopy unit of Larnaca General Hospital during the period from October to November 2012. The criteria for participating in this study were constituted by the documented diagnosis of either ulcerative colitis (UC) or Crohn's disease (CD) after endoscopy and histologic examination at least 6 months before the study, adult patients (18 years old or older), the capability of verbal communication and the patient's written consent for attending this study. The majority of the questionnaires were completed by a nurse practitioner who specializes in IBD patient care.
RESULTS: Regarding the physical dimension in patients with UC, males scored significantly higher than females (4.2 vs 3.4, P = 0.023). Higher scores were also observed in UC patients younger than 35 or older than 50 years (4.0 and 4.2 vs 3.2, respectively, P = 0.021). The psychological dimension revealed similar results in patients with UC, with males, and older ages scoring higher (5.0 vs 3.0, P = 0.01 and 4.7 vs 2.7, P < 0.5, respectively), whereas regarding CD higher scores were observed in married compared to unmarried (3.83 vs 2.33, P = 0.042). No statistical differences in any parameters in the social dimension were observed. Regarding the treatment of, patients with CD, overall higher scores were observed when treated with biological factors compared to standard therapy in all dimensions but with statistical significant difference in the social dimension (5.00 vs 3.25, P = 0.045).
CONCLUSION: The study reveals a negative impact of IBD on HRQoL. Increased risks are age and gender in patients with UC and family status in patients with CD.

Entities:  

Keywords:  Crohn’s disease; Health related quality of life; Quality of life; Short inflammatory bowel disease questionnaire; Ulcerative colitis

Mesh:

Substances:

Year:  2017        PMID: 28104987      PMCID: PMC5221275          DOI: 10.3748/wjg.v23.i1.121

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  27 in total

1.  Factors affecting health related quality of life of patients with inflammatory bowel disease.

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2.  A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

Authors:  S R Targan; S B Hanauer; S J van Deventer; L Mayer; D H Present; T Braakman; K L DeWoody; T F Schaible; P J Rutgeerts
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Review 3.  Controversies surrounding the comorbidity of depression and anxiety in inflammatory bowel disease patients: a literature review.

Authors:  Antonina A Mikocka-Walus; Deborah A Turnbull; Nicole T Moulding; Ian G Wilson; Jane M Andrews; Gerald J Holtmann
Journal:  Inflamm Bowel Dis       Date:  2007-02       Impact factor: 5.325

Review 4.  Inflammatory bowel disease: cause and immunobiology.

Authors:  Daniel C Baumgart; Simon R Carding
Journal:  Lancet       Date:  2007-05-12       Impact factor: 79.321

5.  Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease.

Authors:  K Nordin; L Påhlman; K Larsson; M Sundberg-Hjelm; L Lööf
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6.  Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial.

Authors:  Stephen B Hanauer; Brian G Feagan; Gary R Lichtenstein; Lloyd F Mayer; S Schreiber; Jean Frederic Colombel; Daniel Rachmilewitz; Douglas C Wolf; Allan Olson; Weihang Bao; Paul Rutgeerts
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7.  Health-related quality of life in patients with inflammatory bowel disease five years after the initial diagnosis.

Authors:  T Bernklev; J Jahnsen; E Aadland; J Sauar; T Schulz; I Lygren; M Henriksen; N Stray; O Kjellevold; M Vatn; B Moum
Journal:  Scand J Gastroenterol       Date:  2004-04       Impact factor: 2.423

8.  The influence of demographic and disease-related factors on health-related quality of life in patients with ulcerative colitis.

Authors:  Henrik Hjortswang; Gunnar Järnerot; Bengt Curman; Hanna Sandberg-Gertzén; Curt Tysk; Björn Blomberg; Sven Almer; Magnus Ström
Journal:  Eur J Gastroenterol Hepatol       Date:  2003-09       Impact factor: 2.566

9.  Health-related quality of life in patients with inflammatory bowel disease: a single-center experience.

Authors:  Maria Kalafateli; Christos Triantos; Georgios Theocharis; Dimitra Giannakopoulou; Efstratios Koutroumpakis; Aristidis Chronis; Apostolos Sapountzis; Vasileios Margaritis; Konstantinos Thomopoulos; Vasiliki Nikolopoulou
Journal:  Ann Gastroenterol       Date:  2013

10.  Psychological problems in gastroenterology outpatients: A South Australian experience. Psychological co-morbidity in IBD, IBS and hepatitis C.

Authors:  Antonina A Mikocka-Walus; Deborah A Turnbull; Jane M Andrews; Nicole T Moulding; Ian G Wilson; Hugh Aj Harley; David J Hetzel; Gerald J Holtmann
Journal:  Clin Pract Epidemiol Ment Health       Date:  2008-05-23
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  4 in total

Review 1.  Sex matters: impact on pathogenesis, presentation and treatment of inflammatory bowel disease.

Authors:  Wendy A Goodman; Ian P Erkkila; Theresa T Pizarro
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2020-09-08       Impact factor: 46.802

2.  Disability in Patients with Inflammatory Bowel Disease: Correlations with Quality of Life and Patient's Characteristics.

Authors:  Konstantinos Argyriou; Andreas Kapsoritakis; Konstantinos Oikonomou; Anastassios Manolakis; Eirini Tsakiridou; Spyridon Potamianos
Journal:  Can J Gastroenterol Hepatol       Date:  2017-05-29

3.  The Rating Form of IBD Patient Concerns: Translation, Validation, and First Implementation of the Greek Version.

Authors:  Konstantinos Argyriou; Eleftheria Roma; Andreas Kapsoritakis; Eirini Tsakiridou; Konstantinos Oikonomou; Anastassios Manolakis; Spyridon Potamianos
Journal:  Gastroenterol Res Pract       Date:  2017-04-25       Impact factor: 2.260

4.  Inflammatory bowel diseases: a burden in pediatrics: Case series and a review of the literature.

Authors:  Cristina Oana Mărginean; Lorena Elena Meliţ; Simona Mocanu; Maria Oana Mărginean
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

  4 in total

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