Literature DB >> 28104340

Why new antibiotics are not obviously useful now.

Grégory Dubourg1, Cédric Abat2, Didier Raoult3.   

Abstract

For several years, the threat of antibiotic resistance and its health cost has dramatically risen and various alarming figures have been proposed to illustrate the mortality due to antibiotic resistance. However, predictions concerning different living beings are doomed to failure, as theorised in Alice's 'living croquet' theory. Actors of antibiotic resistance are the doctors, the patient and the bacteria. Considering that animals and the environment are involved, future disasters are unpredictable. Here we evaluate in a rational manner the reliability of scientific sources showing increasing resistance to antibiotics or increasing mortality related to antibiotic resistance, and we finally consider antibiotic resources to face the situation.
Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

Entities:  

Keywords:  Antibiotic resistance; Mortality; Rescue antibiotics

Mesh:

Substances:

Year:  2017        PMID: 28104340     DOI: 10.1016/j.ijantimicag.2016.11.015

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN: 0924-8579            Impact factor:   5.283


  3 in total

1.  Gonorrhea resistance: don't forget the old chaps.

Authors:  D Raoult
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-09-15       Impact factor: 3.267

2.  The Persister Character of Clinical Isolates of Staphylococcus aureus Contributes to Faster Evolution to Resistance and Higher Survival in THP-1 Monocytes: A Study With Moxifloxacin.

Authors:  Tiep K Nguyen; Frédéric Peyrusson; Magali Dodémont; Nhung H Pham; Hoang A Nguyen; Paul M Tulkens; Françoise Van Bambeke
Journal:  Front Microbiol       Date:  2020-11-23       Impact factor: 5.640

Review 3.  An Update on Clinical Burden, Diagnostic Tools, and Therapeutic Options of Staphylococcus aureus.

Authors:  Prakash Narayana Reddy; Krupanidhi Srirama; Vijaya R Dirisala
Journal:  Infect Dis (Auckl)       Date:  2017-05-22
  3 in total

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