Literature DB >> 28103769

Evaluation of Neuroleptic Utilization in the Intensive Care Unit During Transitions of Care.

Brian Gilbert1, James R Morales2, Randi J Searcy2, Donald W Johnson2,3, Jason A Ferreira2,3.   

Abstract

PURPOSE: The purpose of this study was to identify risk factors associated with inappropriate continuation of neuroleptics postdischarge from the intensive care unit (ICU) and hospital.
MATERIALS AND METHODS: A retrospective chart review was performed including all patients greater than 18 years of age who received neuroleptic medications in an ICU.
RESULTS: One hundred sixty-one patients were included during the 12- month study period. There were 85 (53%) patients discharged from the ICU with inappropriate continuation of a neuroleptic medication. There were 54 (34%) patients discharged from the hospital with inappropriate continuation of a neuroleptic medication. Patients were more likely to be discharged from the ICU with an inappropriate neuroleptic if they were prescribed multiple neuroleptics ( P = .02), did not have a urine drug screen collected at admission ( P = .023), or if trazodone was utilized in their therapy ( P = .004). Patients were more likely to be discharged from the hospital with a neuroleptic if they had multiple neuroleptic orders ( P = .0001) or if trazodone was utilized in their therapy ( P = .0023).
CONCLUSION: Risk factors associated with the continuation of inappropriate neuroleptic medications upon discharge from the ICU or the hospital include multiple neuroleptic medications prescribed, the lack of a urine drug screen upon admission, and the utilization of trazodone.

Entities:  

Keywords:  critical care; intensive care unit; interhospital transfer; quality; safety

Mesh:

Substances:

Year:  2016        PMID: 28103769     DOI: 10.1177/0885066615622424

Source DB:  PubMed          Journal:  J Intensive Care Med        ISSN: 0885-0666            Impact factor:   3.510


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Review 3.  Psychotropic drug therapy in patients in the intensive care unit - usage, adverse effects, and drug interactions: a review.

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4.  The effect of a medication reconciliation program in two intensive care units in the Netherlands: a prospective intervention study with a before and after design.

Authors:  Liesbeth B E Bosma; Nicole G M Hunfeld; Rogier A M Quax; Edmé Meuwese; Piet H G J Melief; Jasper van Bommel; SiokSwan Tan; Maaike J van Kranenburg; Patricia M L A van den Bemt
Journal:  Ann Intensive Care       Date:  2018-02-07       Impact factor: 6.925

  4 in total

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