| Literature DB >> 28102684 |
Shaofang Zhou1, Tao Song1, He Chen1, Zhonglin Liu1, Haigen Shen1, Chaozhong Li1,2.
Abstract
The trifluoromethylalkynylation of unactivated alkenes with alkynyl sulfones and Togni's reagent was developed. The reaction was catalyzed by 2,4,6-trimethylpyridine, leading to various β-trifluoromethylated alkynes under metal-free conditions with a broad substrate scope and wide functional group compatibility. A mechanism involving catalytic nonchain radical processes is proposed.Entities:
Year: 2017 PMID： 28102684 DOI： 10.1021/acs.orglett.6b03870
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005