B L Vanderbyl1, M J Mayer2, C Nash1, A T Tran1,3, T Windholz1, T Swanson1, G Kasymjanova3, R T Jagoe4,5. 1. McGill Cancer Nutrition Rehabilitation Program, Segal Cancer Centre, Jewish General Hospital, Room E-809, 3755 Ch de la Cote-Sainte-Catherine, Montreal, QC, H3T 1E2, Canada. 2. School of Kinesiology and Physical Education, McGill University, Montreal, Canada. 3. Peter Brojde Lung Cancer Centre, Segal Cancer Centre, Jewish General Hospital, Montreal, Canada. 4. McGill Cancer Nutrition Rehabilitation Program, Segal Cancer Centre, Jewish General Hospital, Room E-809, 3755 Ch de la Cote-Sainte-Catherine, Montreal, QC, H3T 1E2, Canada. thomas.jagoe@mcgill.ca. 5. Peter Brojde Lung Cancer Centre, Segal Cancer Centre, Jewish General Hospital, Montreal, Canada. thomas.jagoe@mcgill.ca.
Abstract
PURPOSE:Patients with advanced cancer frequentlyexperience anxiety, depression and poor quality of life (QOL), as well as physical symptoms such as fatigue and weakness. Physical exercise has potential to help control these symptoms but the optimal training prescription is still not clear. We performed a study comparing medical Qigong (QG) and standard endurance and strength training (SET) in patients with advanced stage non-small cell lung (NSCLC) and gastrointestinal (GI) cancers. METHODS: A randomized, cross-over study was performed in patients with advanced NSCLC and GI cancers receiving or eligible for chemotherapy. Patients received supervised QG or SET twice-weekly for 6 weeks. Psychological functioning, QOL, symptoms and physical functioning were assessed before and after each intervention period. RESULTS:Nineteen patients completed both interventions. Comparing interventions revealed no difference between QG and SET on change in anxiety or depression scores or QOL. However, SET treatment was better at improving perceived strength (P = 0.05) and walking distance (P = 0.02). The order in which interventions were performed had a significant impact on the improvement in certain symptoms (sleep quality, breathlessness, P < 0.05), QOL (P = 0.01) and walking distance (P = 0.008). In all cases, the beneficial effects of the exercise interventions were markedly reduced during the second interval. CONCLUSIONS: QG and SET are equivalent in their impact on many aspects of psychological function in cancer patients. However, SET leads to greater improvements in exercise capacity and helps reduce some symptoms. The reduction in beneficial effect of SET on exercise function when offered as the second intervention is a new finding that warrants further study.
RCT Entities:
PURPOSE:Patients with advanced cancer frequently experience anxiety, depression and poor quality of life (QOL), as well as physical symptoms such as fatigue and weakness. Physical exercise has potential to help control these symptoms but the optimal training prescription is still not clear. We performed a study comparing medical Qigong (QG) and standard endurance and strength training (SET) in patients with advanced stage non-small cell lung (NSCLC) and gastrointestinal (GI) cancers. METHODS: A randomized, cross-over study was performed in patients with advanced NSCLC and GI cancers receiving or eligible for chemotherapy. Patients received supervised QG or SET twice-weekly for 6 weeks. Psychological functioning, QOL, symptoms and physical functioning were assessed before and after each intervention period. RESULTS: Nineteen patients completed both interventions. Comparing interventions revealed no difference between QG and SET on change in anxiety or depression scores or QOL. However, SET treatment was better at improving perceived strength (P = 0.05) and walking distance (P = 0.02). The order in which interventions were performed had a significant impact on the improvement in certain symptoms (sleep quality, breathlessness, P < 0.05), QOL (P = 0.01) and walking distance (P = 0.008). In all cases, the beneficial effects of the exercise interventions were markedly reduced during the second interval. CONCLUSIONS: QG and SET are equivalent in their impact on many aspects of psychological function in cancerpatients. However, SET leads to greater improvements in exercise capacity and helps reduce some symptoms. The reduction in beneficial effect of SET on exercise function when offered as the second intervention is a new finding that warrants further study.
Entities:
Keywords:
Advanced cancer; Exercise; Functional capacity; Medical qigong; Quality of life; Rehabilitation
Authors: Lis Adamsen; Morten Quist; Julie Midtgaard; Christina Andersen; Tom Møller; Lasse Knutsen; Anders Tveterås; Mikael Rorth Journal: Support Care Cancer Date: 2005-08-12 Impact factor: 3.603
Authors: Shiraz I Mishra; Roberta W Scherer; Claire Snyder; Paula M Geigle; Debra R Berlanstein; Ozlem Topaloglu Journal: Cochrane Database Syst Rev Date: 2012-08-15
Authors: Bihiyga Salhi; Christel Haenebalcke; Silvia Perez-Bogerd; Mai D Nguyen; Vincent Ninane; Thomas L A Malfait; Karim Y Vermaelen; Veerle F Surmont; Georges Van Maele; Roos Colman; Eric Derom; Jan P van Meerbeeck Journal: Lung Cancer Date: 2015-05-22 Impact factor: 5.705
Authors: Morten Quist; Lis Adamsen; Mikael Rørth; Jørgen H Laursen; Karl B Christensen; Seppo W Langer Journal: Integr Cancer Ther Date: 2015-03-22 Impact factor: 3.279
Authors: D Jastrzębski; M Maksymiak; S Kostorz; B Bezubka; I Osmanska; T Młynczak; A Rutkowska; Z Baczek; D Ziora; J Kozielski Journal: Adv Exp Med Biol Date: 2015 Impact factor: 2.622
Authors: Giorgio Vittorio Scagliotti; Purvish Parikh; Joachim von Pawel; Bonne Biesma; Johan Vansteenkiste; Christian Manegold; Piotr Serwatowski; Ulrich Gatzemeier; Raghunadharao Digumarti; Mauro Zukin; Jin S Lee; Anders Mellemgaard; Keunchil Park; Shehkar Patil; Janusz Rolski; Tuncay Goksel; Filippo de Marinis; Lorinda Simms; Katherine P Sugarman; David Gandara Journal: J Clin Oncol Date: 2008-05-27 Impact factor: 44.544
Authors: G B Stene; J L Helbostad; T R Balstad; I I Riphagen; S Kaasa; L M Oldervoll Journal: Crit Rev Oncol Hematol Date: 2013-08-09 Impact factor: 6.312
Authors: Peter M Wayne; M S Lee; J Novakowski; K Osypiuk; J Ligibel; L E Carlson; R Song Journal: J Cancer Surviv Date: 2017-12-08 Impact factor: 4.442
Authors: Antonio Jose Grande; Valter Silva; Larissa Sawaris Neto; João Pedro Teixeira Basmage; Maria S Peccin; Matthew Maddocks Journal: Cochrane Database Syst Rev Date: 2021-03-18
Authors: Wendy Wing Yan So; Erin Yiqing Lu; Wai Ming Cheung; Hector Wing Hong Tsang Journal: Int J Environ Res Public Health Date: 2020-11-23 Impact factor: 3.390