Literature DB >> 28102027

Patient engagement in HIV care and treatment in Zambia, 2004-2014.

Neo Christopher Chung1,2, Carolyn Bolton-Moore1,3, Roma Chilengi1,2, Margaret P Kasaro2, Jeffrey S A Stringer2, Benjamin H Chi2.   

Abstract

OBJECTIVE: To describe engagement along the HIV continuum of care using a large network of clinics in Zambia.
METHODS: We employed a practical framework to describe retention along the HIV treatment cascade, using routinely collected clinical data available in resource-constrained settings. We included health facilities in four Zambian provinces with more than 300 enrolled patients over the age of 5 years. We described attrition at each step, from HIV enrolment to 720 days after ART initiation. The population was further stratified by year of enrolment to describe temporal trends in patient engagement.
RESULTS: From January 2004 to December 2014, 444 439 individuals over the age of 5 years sought HIV care at 75 eligible health facilities. Among those enrolled into HIV care, 82.1% (95% confidence interval [CI]: 79.4-84.5%) were fully assessed for ART eligibility within 180 days of enrolment and 63.6% (95% CI: 61.7-65.3) were found to be eligible for ART based on the HIV treatment guidelines at the time. Of those patients eligible for ART, 81.1% (95% CI: 79.5-82.7%) initiated ART within 180 days. Patient retention in ART programme was 81.2% (95% CI: 80.4-81.9%) at 90 days, 70.0% (95% CI: 68.7-71.2%) at 360 days and 61.6% (95% CI: 60.0-63.2%) at 720 days. We noted a steady decline in proportions assessed for ART eligibility and deemed eligible for ART in the time frame. Proportions that started ART and remained in care remained relatively consistent.
CONCLUSION: We describe a simple approach for assessing patient engagement after enrolment into HIV care. Using limited types of data routinely available, we demonstrate an important and replicable approach to monitoring programmes in resource-constrained settings.
© 2017 John Wiley & Sons Ltd.

Entities:  

Keywords:  Africa; HIV; Zambia; cascade; continuum of care; treatment

Mesh:

Substances:

Year:  2017        PMID: 28102027      PMCID: PMC6506213          DOI: 10.1111/tmi.12832

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  37 in total

1.  Nonadherence to medical appointments is associated with increased plasma HIV RNA and decreased CD4 cell counts in a community-based HIV primary care clinic.

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Journal:  AIDS Care       Date:  2005-10

2.  Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countries.

Authors:  Elizabeth M Stringer; Benjamin H Chi; Namwinga Chintu; Tracy L Creek; Didier K Ekouevi; David Coetzee; Pius Tih; Andrew Boulle; Francois Dabis; Nathan Shaffer; Catherine M Wilfert; Jeffrey S A Stringer
Journal:  Bull World Health Organ       Date:  2008-01       Impact factor: 9.408

3.  Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes.

Authors:  Jeffrey S A Stringer; Isaac Zulu; Jens Levy; Elizabeth M Stringer; Albert Mwango; Benjamin H Chi; Vilepe Mtonga; Stewart Reid; Ronald A Cantrell; Marc Bulterys; Michael S Saag; Richard G Marlink; Alwyn Mwinga; Tedd V Ellerbrock; Moses Sinkala
Journal:  JAMA       Date:  2006-08-16       Impact factor: 56.272

4.  Missed visits and mortality among patients establishing initial outpatient HIV treatment.

Authors:  Michael J Mugavero; Hui-Yi Lin; James H Willig; Andrew O Westfall; Kimberly B Ulett; Justin S Routman; Sarah Abroms; James L Raper; Michael S Saag; Jeroan J Allison
Journal:  Clin Infect Dis       Date:  2009-01-15       Impact factor: 9.079

5.  Retention in care: a challenge to survival with HIV infection.

Authors:  Thomas P Giordano; Allen L Gifford; A Clinton White; Maria E Suarez-Almazor; Linda Rabeneck; Christine Hartman; Lisa I Backus; Larry A Mole; Robert O Morgan
Journal:  Clin Infect Dis       Date:  2007-04-23       Impact factor: 9.079

6.  Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia.

Authors:  Carolyn Bolton-Moore; Mwangelwa Mubiana-Mbewe; Ronald A Cantrell; Namwinga Chintu; Elizabeth M Stringer; Benjamin H Chi; Moses Sinkala; Chipepo Kankasa; Craig M Wilson; Catherine M Wilfert; Albert Mwango; Jens Levy; Elaine J Abrams; Marc Bulterys; Jeffrey S A Stringer
Journal:  JAMA       Date:  2007-10-24       Impact factor: 56.272

7.  Sampling-based approach to determining outcomes of patients lost to follow-up in antiretroviral therapy scale-up programs in Africa.

Authors:  Elvin H Geng; Nneka Emenyonu; Mwebesa Bosco Bwana; David V Glidden; Jeffrey N Martin
Journal:  JAMA       Date:  2008-08-06       Impact factor: 56.272

8.  Community-based follow-up for late patients enrolled in a district-wide programme for antiretroviral therapy in Lusaka, Zambia.

Authors:  D W Krebs; B H Chi; Y Mulenga; M Morris; R A Cantrell; L Mulenga; J Levy; M Sinkala; J S A Stringer
Journal:  AIDS Care       Date:  2008-03

9.  Simple adherence assessments to predict virologic failure among HIV-infected adults with discordant immunologic and clinical responses to antiretroviral therapy.

Authors:  Jason D Goldman; Ronald A Cantrell; Lloyd B Mulenga; Bushimbwa C Tambatamba; Stewart E Reid; Jens W Levy; Mohammed Limbada; Angela Taylor; Michael S Saag; Sten H Vermund; Jeffrey S A Stringer; Benjamin H Chi
Journal:  AIDS Res Hum Retroviruses       Date:  2008-08       Impact factor: 2.205

Review 10.  Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review.

Authors:  Sydney Rosen; Matthew P Fox; Christopher J Gill
Journal:  PLoS Med       Date:  2007-10-16       Impact factor: 11.069

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  3 in total

1.  Patient Transfers and Their Impact on Gaps in Clinical Care: Differences by Gender in a Large Cohort of Adults Living with HIV on Antiretroviral Therapy in South Africa.

Authors:  Angela M Bengtson; Ana Lucia Espinosa Dice; Kipruto Kirwa; Morna Cornell; Christopher J Colvin; Mark N Lurie
Journal:  AIDS Behav       Date:  2021-02-20

2.  Developing and implementing national health identifiers in resource limited countries: why, what, who, when and how?

Authors:  Eduard J Beck; J Mark Shields; Gaurang Tanna; Gerrit Henning; Ian de Vega; Gail Andrews; Philippe Boucher; Lionel Benting; Jesus Maria Garcia-Calleja; John Cutler; Whitney Ewing; Boonchai Kijsanayotin; Tapiwanashe Kujinga; Mary Mahy; Keletso Makofane; Kim Marsh; Chujit Nacheeva; Noma Rangana; Mary Felissa Reyes Vega; Keith Sabin; Olga Varetska; Steven Macharia Wanyee; Stephen Watiti; Brian Williams; Jinkou Zhao; Cesar Nunez; Peter Ghys; Daniel Low-Beer
Journal:  Glob Health Action       Date:  2018       Impact factor: 2.640

3.  Progress in the performance of HIV early infant diagnosis services in Zambia using routinely collected data from 2006 to 2016.

Authors:  Jasleen Singh; Suzanne Filteau; Jim Todd; Sehlulekile Gumede-Moyo
Journal:  BMC Public Health       Date:  2018-11-26       Impact factor: 3.295

  3 in total

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