Literature DB >> 28101185

Hypokalemic myopathy in primary aldosteronism: A case report.

Chuifen Wu1, Jun Xin2, Minghua Xin2, Hai Zou3, Lie Jing3, Caoyong Zhu3, Wenhui Lei3.   

Abstract

Primary aldosteronism (PA) is a rare disorder. The majority of patients with PA present with typical features and are easily diagnosed. This disorder is usually diagnosed with hypokalemia, hypertension or an adrenal mass. However, patients with atypical symptoms may present a challenge for diagnosis and treatment. In the present study, a case of PA is described that presented with hypokalemic myopathy simulating polymyositis. The patient was a 44-year-old woman who presented with weakness and difficulty walking. The patient was initially suspected to have PM and was treated with methylprednisolone. The patient was found to have hypokalemia which persisted despite high-dose supplementation of potassium. Adrenal computed tomography revealed a right adrenal mass. Surgical adrenalectomy was conducted. The final pathological diagnosis was benign adrenocortical adenoma. The serum tests remained normal and the patient's symptoms were resolved during the 8-month follow-up.

Entities:  

Keywords:  hypokalemic myopathy; primary aldosteronism

Year:  2016        PMID: 28101185      PMCID: PMC5228118          DOI: 10.3892/etm.2016.3864

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  10 in total

1.  Clinical features and recovery patterns of acquired non-thyrotoxic hypokalemic paralysis.

Authors:  Akiyuki Hiraga; Ikuo Kamitsukasa; Kazuho Kojima; Satoshi Kuwabara
Journal:  J Neurol Sci       Date:  2011-10-13       Impact factor: 3.181

2.  Primary aldosteronism simulating polymyositis.

Authors:  Yan-Chun Tang; Shao-Kun Wang; Wei-Ling Yuan
Journal:  J Rheumatol       Date:  2011-07       Impact factor: 4.666

3.  Fifty cases of primary hyperaldosteronism in Hong Kong Chinese with a high frequency of periodic paralysis. Evaluation of techniques for tumour localisation.

Authors:  J T Ma; C Wang; K S Lam; R T Yeung; F L Chan; J Boey; P S Cheung; J P Coghlan; B A Scoggins; J R Stockigt
Journal:  Q J Med       Date:  1986-11

Review 4.  [A case of primary aldosteronism presenting hypokalemic myopathy induced by benidipine hydrochloride; a dihydropyridine calcium channel blocker].

Authors:  H Sugawara; H Shiraiwa; M Otsuka; A Ueki
Journal:  Rinsho Shinkeigaku       Date:  2000-05

5.  Primary aldosteronism associated with severe rhabdomyolysis due to profound hypokalemia.

Authors:  Atsushi Goto; Yoshihiko Takahashi; Miyako Kishimoto; Shigeru Minowada; Hitoshi Aibe; Kanehiro Hasuo; Hiroshi Kajio; Mitsuhiko Noda
Journal:  Intern Med       Date:  2009-02-16       Impact factor: 1.271

6.  The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline.

Authors:  John W Funder; Robert M Carey; Franco Mantero; M Hassan Murad; Martin Reincke; Hirotaka Shibata; Michael Stowasser; William F Young
Journal:  J Clin Endocrinol Metab       Date:  2016-03-02       Impact factor: 5.958

7.  Polymyositis with hypokalemia: correction with potassium replacement in the absence of steroids.

Authors:  N J Becker; M Hinman; M N Giles; J J Kepes; N I Abdou
Journal:  J Rheumatol       Date:  1987-10       Impact factor: 4.666

8.  Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.

Authors:  John W Funder; Robert M Carey; Carlos Fardella; Celso E Gomez-Sanchez; Franco Mantero; Michael Stowasser; William F Young; Victor M Montori
Journal:  J Clin Endocrinol Metab       Date:  2008-06-13       Impact factor: 5.958

Review 9.  Inflammatory Myopathies.

Authors:  Rama Bandlamudi Atluri
Journal:  Mo Med       Date:  2016 Mar-Apr

10.  Hypokalemia induced myopathy as first manifestation of primary hyperaldosteronism - an elderly patient with unilateral adrenal hyperplasia: a case report.

Authors:  Panagiotis Kotsaftis; Christos Savopoulos; Dimitrios Agapakis; George Ntaios; Valentini Tzioufa; Vasilios Papadopoulos; Epaminondas Fahantidis; Apostolos Hatzitolios
Journal:  Cases J       Date:  2009-07-16
  10 in total
  1 in total

1.  Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases.

Authors:  Chung-Tso Chen; Yen-Chieh Wang; Chih-Ming Lin
Journal:  Am J Case Rep       Date:  2021-04-10
  1 in total

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