Literature DB >> 28100409

Effect of thymectomy for thymic atrophy in myasthenia gravis: A retrospective study on 93 patients.

Keiichi Nakahara1, Shunya Nakane2, Makoto Nakajima3, Satoshi Yamashita4, Takeshi Mori5, Yukio Ando6.   

Abstract

To clarify the efficacy of thymectomy among myasthenia gravis (MG) patients with and without thymoma. We classified MG patients who underwent thymectomy into 3 groups, such as thymic atrophy group, thymic follicular hyperplasia (TFH) group and thymoma group. We compared the data of clinical features and postoperative prognosis at very short-term, short-term, and medium-term. The clinical course of MG patients with atrophic thymus after thymectomy was even better than those of TFH or thymoma, in this retrospective study. However, we found no significant differences in the comparison of mean dose of prednisolone between the 3 groups at each time point.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anti-acetylcholine receptor antibody; Myasthenia gravis; Prednisolone; Thymectomy; Thymus pathology

Mesh:

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Year:  2017        PMID: 28100409     DOI: 10.1016/j.jneuroim.2017.01.005

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN: 0165-5728            Impact factor:   3.478


  2 in total

1.  Effects of thymectomy on late-onset non-thymomatous myasthenia gravis: systematic review and meta-analysis.

Authors:  Jinwei Zhang; Yuan Chen; Hui Zhang; Zhaoyu Yang; Peng Zhang
Journal:  Orphanet J Rare Dis       Date:  2021-05-20       Impact factor: 4.123

2.  Effect of thymectomy in elderly patients with non-thymomatous generalized myasthenia gravis.

Authors:  Seung Woo Kim; Young-Chul Choi; Seung Min Kim; Hyo Sup Shim; Ha Young Shin
Journal:  J Neurol       Date:  2019-02-06       Impact factor: 4.849

  2 in total

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