| Literature DB >> 28099863 |
Abstract
Mechanisms that govern PD1 expression and exhaustion in T cells are not fully understood. In this issue of Immunity, Stephen et al. (2017) uncover a key role for the genome organizer Satb1 in restraining PD1 expression and promoting tumor immunity.Entities:
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Year: 2017 PMID: 28099863 DOI: 10.1016/j.immuni.2017.01.002
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745