Literature DB >> 28098996

Ulapualides C-E Isolated from a Hawaiian Hexabranchus sanguineus Egg Mass.

Stephen M Parrish1, Wesley Yoshida1, Baojun Yang2, Philip G Williams1,2.   

Abstract

Three new ulapualides (3-5) were isolated from egg masses of the nudibranch Hexabranchus sanguineus. The structures of 3-5 were deduced by analyses of physical and spectroscopic data in comparisons with ulapualides A (1) and B (2). Ulapualide C demonstrated submicromolar cytotoxicity against select NCI cell lines (768-0, DU-145, MDA-MB-231, and A549) with the most potent activity against MDA-MB-231 cells (IC50 0.58 μM). Ulapualides A (1) and B (2) were 2- to 4-fold more potent than 3.

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Year:  2017        PMID： 28098996      PMCID： PMC5365346          DOI： 10.1021/acs.jnatprod.6b00896

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Absolute stereochemistry of ulapualide A.

Authors:  John S Allingham; Junichi Tanaka; Gerard Marriott; Ivan Rayment
Journal:  Org Lett       Date:  2004-02-19       Impact factor: 6.005

2.  Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae.

Authors:  Makoto Kitamura; Peter J Schupp; Yoshikatsu Nakano; Daisuke Uemura
Journal:  Tetrahedron Lett       Date:  2009-11-25       Impact factor: 2.415

3.  Evidence for the biosynthesis of bryostatins by the bacterial symbiont "Candidatus Endobugula sertula" of the bryozoan Bugula neritina.

Authors:  S K Davidson; S W Allen; G E Lim; C M Anderson; M G Haygood
Journal:  Appl Environ Microbiol       Date:  2001-10       Impact factor: 4.792

4.  Tolytoxin and new scytophycins from three species of Scytonema.

Authors:  S Carmeli; R E Moore; G M Patterson
Journal:  J Nat Prod       Date:  1990 Nov-Dec       Impact factor: 4.050

5.  Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin.

Authors:  Vadim A Klenchin; John S Allingham; Ryan King; Junichi Tanaka; Gerard Marriott; Ivan Rayment
Journal:  Nat Struct Biol       Date:  2003-10-26

6.  Biomolecular mimicry in the actin cytoskeleton: mechanisms underlying the cytotoxicity of kabiramide C and related macrolides.

Authors:  Junichi Tanaka; Yuling Yan; Jeongeun Choi; Jihong Bai; Vadim A Klenchin; Ivan Rayment; Gerard Marriott
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-11       Impact factor: 11.205

7.  Structure elucidation at the nanomole scale. 1. Trisoxazole macrolides and thiazole-containing cyclic peptides from the nudibranch Hexabranchus sanguineus.

Authors:  Doralyn S Dalisay; Evan W Rogers; Arthur S Edison; Tadeusz F Molinski
Journal:  J Nat Prod       Date:  2009-04       Impact factor: 4.050

8.  Localization of 'Candidatus Endobugula sertula' and the bryostatins throughout the life cycle of the bryozoan Bugula neritina.

Authors:  Koty H Sharp; Seana K Davidson; Margo G Haygood
Journal:  ISME J       Date:  2007-10-11       Impact factor: 10.302
  8 in total
  3 in total

Review 1.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

Review 2.  High-value compounds from the molluscs of marine and estuarine ecosystems as prospective functional food ingredients: An overview.

Authors:  Kajal Chakraborty; Minju Joy
Journal:  Food Res Int       Date:  2020-08-31       Impact factor: 6.475

Review 3.  The Potential of Indonesian Heterobranchs Found around Bunaken Island for the Production of Bioactive Compounds.

Authors:  Katja M Fisch; Cora Hertzer; Nils Böhringer; Zerlina G Wuisan; Dorothee Schillo; Robert Bara; Fontje Kaligis; Heike Wägele; Gabriele M König; Till F Schäberle
Journal:  Mar Drugs       Date:  2017-12-07       Impact factor: 5.118
  3 in total

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