Literature DB >> 28098391

Understanding the formidable nail barrier: A review of the nail microstructure, composition and diseases.

Sudhir Baswan1,2, Gerald B Kasting1, S Kevin Li1, Randy Wickett1, Brian Adams3, Sean Eurich2, Ryan Schamper2.   

Abstract

The topical treatment of nail fungal infections has been a focal point of nail research in the past few decades as it offers a much safer and focused alternative to conventional oral therapy. Although the current focus remains on exploring the ways of enhancing permeation through the formidable nail barrier, the understanding of the nail microstructure and composition is far from complete. This article reviews our current understanding of the nail microstructure, composition and diseases. A few of the parameters affecting the nail permeability and potential causes of the recurrence of fungal nail infection are also discussed.
© 2017 Blackwell Verlag GmbH.

Entities:  

Keywords:  anti-fungal; iontophoresis; keratin; laser treatment; nails; onychomycosis

Mesh：

Substances：

Year:  2017        PMID： 28098391      PMCID： PMC5383514          DOI： 10.1111/myc.12592

Source DB:  PubMed          Journal:  Mycoses        ISSN： 0933-7407            Impact factor:   4.377


  94 in total

Review 1.  Structure and biochemistry of mammalian hard keratin.

Authors:  R C Marshall; D F Orwin; J M Gillespie
Journal:  Electron Microsc Rev       Date:  1991

2.  A few aspects of transonychial water loss (TOWL): inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish.

Authors:  Sudaxshina Murdan; Dhrumit Hinsu; Marie Guimier
Journal:  Eur J Pharm Biopharm       Date:  2008-06-06       Impact factor: 5.571

3.  A comparative study of the physicochemical properties of human keratinized tissues.

Authors:  H P Baden; L A Goldsmith; B Fleming
Journal:  Biochim Biophys Acta       Date:  1973-10-18

4.  Detection of amphetamines in fingernails: an alternative to hair analysis.

Authors:  V Cirimele; P Kintz; P Mangin
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

5.  Physicochemical characterization of the human nail: solvent effects on the permeation of homologous alcohols.

Authors:  K A Walters; G L Flynn; J R Marvel
Journal:  J Pharm Pharmacol       Date:  1985-11       Impact factor: 3.765

6.  Monitoring of cadmium, copper, lead and zinc status in young children using toenails: comparison with scalp hair.

Authors:  M Wilhelm; D Hafner; I Lombeck; F K Ohnesorge
Journal:  Sci Total Environ       Date:  1991-04-15       Impact factor: 7.963

7.  Iontophoretic delivery of terbinafine in onychomycosis: a preliminary study.

Authors:  B Amichai; B Nitzan; R Mosckovitz; A Shemer
Journal:  Br J Dermatol       Date:  2009-07-20       Impact factor: 9.302

8.  Molecular analysis of dermatophytes suggests spread of infection among household members.

Authors:  Mahmoud A Ghannoum; Pranab K Mukherjee; Erin M Warshaw; Scott Evans; Neil J Korman; Amir Tavakkol
Journal:  Cutis       Date:  2013-05

Review 9.  Onychomycosis--epidemiology, diagnosis and management.

Authors:  R Kaur; B Kashyap; P Bhalla
Journal:  Indian J Med Microbiol       Date:  2008 Apr-Jun       Impact factor: 0.985

10.  Iontophoretically enhanced ciclopirox delivery into and across human nail plate.

Authors:  Jinsong Hao; Kelly A Smith; S Kevin Li
Journal:  J Pharm Sci       Date:  2009-10       Impact factor: 3.534
View more
  16 in total

1.  Comparative Study of Traditional Ablative CO2 Laser-Assisted Topical Antifungal with only Topical Antifungal for Treating Onychomycosis: A Multicenter Study.

Authors:  Bhavana Rajbanshi; Liangliang Shen; Miao Jiang; Qingyu Gao; Xin Huang; Jiaoyang Ma; Jihong Wang; Yang Hu; Hongli Lv; Xiao Wu; Jingjun Zhao
Journal:  Clin Drug Investig       Date:  2020-06       Impact factor: 2.859

2.  Iontophoresis application for drug delivery in high resistivity membranes: nails and teeth.

Authors:  Jayanaraian F Martins Andrade; Thamires da Cunha Miranda; Marcílio Cunha-Filho; Stephânia Fleury Taveira; Guilherme M Gelfuso; Taís Gratieri
Journal:  Drug Deliv Transl Res       Date:  2022-10-08       Impact factor: 5.671

3.  Topical anesthetic analgesic therapy using the combination of ropivacaine and dexmedetomidine: hyaluronic acid modified long-acting nanostructured lipid carriers containing a skin penetration enhancer.

Authors:  Yongjian Yang; Dahai Qiu; Yajun Liu; Lei Chao
Journal:  Drug Des Devel Ther       Date:  2019-09-18       Impact factor: 4.162

Review 4.  Challenge of Nail Psoriasis: An Update Review.

Authors:  Chao Ji; Haiqing Wang; Chengbei Bao; Liangliang Zhang; Shifan Ruan; Jing Zhang; Ting Gong; Bo Cheng
Journal:  Clin Rev Allergy Immunol       Date:  2021-09-03       Impact factor: 8.667

5.  Propolis Extract for Onychomycosis Topical Treatment: From Bench to Clinic.

Authors:  Flavia F Veiga; Marina C Gadelha; Marielen R T da Silva; Maiara I Costa; Brenda Kischkel; Lidiane V de Castro-Hoshino; Francielle Sato; Mauro L Baesso; Morgana F Voidaleski; Vanessa Vasconcellos-Pontello; Vânia A Vicente; Marcos L Bruschi; Melyssa Negri; Terezinha I E Svidzinski
Journal:  Front Microbiol       Date:  2018-04-25       Impact factor: 5.640

6.  Improved Methods for Assessing Therapeutic Potential of Antifungal Agents against Dermatophytes and Their Application in the Development of NP213, a Novel Onychomycosis Therapy Candidate.

Authors:  Derry K Mercer; Colin S Stewart; Lorna Miller; Jennifer Robertson; Vanessa M S Duncan; Deborah A O'Neil
Journal:  Antimicrob Agents Chemother       Date:  2019-04-25       Impact factor: 5.191

7.  Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth.

Authors:  Hye Su Kim; Ha-Kyoung Kwon; Dong Hoon Lee; Thao Nguyen Le; Hye-Jin Park; Moon Il Kim
Journal:  Int J Nanomedicine       Date:  2019-10-22

8.  In-vitro Detection of Phytopathogenic Fungal Cell Wall by Polyclonal Sera Raised Against Trimethyl Chitosan Nanoparticles.

Authors:  Hemant Joshi; Anshu Malik; Soumya Aggarwal; Manoj Munde; Subhrangsu Sundar Maitra; Nidhi Adlakha; Rakesh Bhatnagar
Journal:  Int J Nanomedicine       Date:  2019-12-20

9.  Ultrasound Evaluation of the Effectiveness of the Use of Acitretin in the Treatment of Nail Psoriasis.

Authors:  Magdalena Krajewska-Włodarczyk; Zbigniew Żuber; Agnieszka Owczarczyk-Saczonek
Journal:  J Clin Med       Date:  2021-05-14       Impact factor: 4.241

10.  Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer.

Authors:  Elena Cutrín-Gómez; Soledad Anguiano-Igea; M Begoña Delgado-Charro; José Luis Gómez-Amoza; Francisco J Otero-Espinar
Journal:  Pharmaceutics       Date:  2018-09-11       Impact factor: 6.321
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.