Literature DB >> 28097276

Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells.

Arthur H A M van Onzen1, Lorenzo Albertazzi2, Albertus P H J Schenning3, Lech-Gustav Milroy1, Luc Brunsveld1.   

Abstract

The fate of small molecule nanoparticles (SMNPs) composed of self-assembling intrinsically fluorescent π-conjugated oligomers was studied in cells as a function of side-chain hydrophobicity. While the hydrophobic SMNPs remained intact upon cellular uptake, the more hydrophilic SMNPs disassembled and dispersed throughout the cytosol.

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Year:  2017        PMID： 28097276     DOI： 10.1039/c6cc08793k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Tetrazine- trans-Cyclooctene Chemistry Applied to Fabricate Self-Assembled Fluorescent and Radioactive Nanoparticles for in Vivo Dual Mode Imaging.

Authors:  Arthur H A M van Onzen; Raffaella Rossin; Albertus P H J Schenning; Klaas Nicolay; Lech-Gustav Milroy; Marc S Robillard; Luc Brunsveld
Journal:  Bioconjug Chem       Date:  2019-02-12       Impact factor: 4.774

Review 2.  How the Physicochemical Properties of Manufactured Nanomaterials Affect Their Performance in Dispersion and Their Applications in Biomedicine: A Review.

Authors:  Spiros H Anastasiadis; Kiriaki Chrissopoulou; Emmanuel Stratakis; Paraskevi Kavatzikidou; Georgia Kaklamani; Anthi Ranella
Journal:  Nanomaterials (Basel)       Date:  2022-02-06       Impact factor: 5.076

3.  Fluorene benzothiadiazole co-oligomer based aqueous self-assembled nanoparticles.

Authors:  J Schill; L Ferrazzano; A Tolomelli; A P H J Schenning; L Brunsveld
Journal:  RSC Adv       Date:  2020-01-02       Impact factor: 4.036
  3 in total

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