Literature DB >> 28096925

Penile metastasis from primary transitional cell carcinoma of the bladder sparing the urethra.

Justin D Oake1, Douglas N Drover2.   

Abstract

Metastatic involvement of the penis is relatively infrequent. Metastasis of transitional cell carcinoma (TCC) is extremely rare. We report a case of bladder TCC with metastases to the penis that spares the urethra - a finding that, to the best of our knowledge, has not been previously reported. Of the documented mechanisms of metastatic transmission to the penis, we suspect the cause was retrograde lymphatic spread. In our case, a 59-year-old male presented to our clinic initially with phimosis and later developed gross hematuria. Subsequent cystoscopy noted the appearance of tumour extending into the prostate, as well as the appearance of extensive TCC throughout the bladder. Following transurethral resection of prostate and bladder tissue, which demonstrated high-grade urothelial carcinoma, the patient underwent a radical cystoprostatectomy. A year later, he developed worsening gross hematuria and we noted the appearance of primary penile squamous cell malignancy. He then underwent a partial penectomy. The histopathology evaluation result from the partial penectomy revealed infiltration of TCC in the glans penis, as well as invasion into the corpus spongiosum, with sparing of the urethra.

Entities:  

Year:  2016        PMID: 28096925      PMCID: PMC5234407          DOI: 10.5489/cuaj.3532

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  10 in total

1.  Cutaneous metastatic carcinoma of the penis: suspected metastasis implantation from a bladder tumor.

Authors:  T Miyamoto; A Ikehara; M Araki; T Akaeda; M Mihara
Journal:  J Urol       Date:  2000-05       Impact factor: 7.450

Review 2.  Late penile metastasis from primary bladder carcinoma.

Authors:  Andreas P Berger; Hermann Rogatsch; Lorenz Hoeltl; Hannes Steiner; Georg Bartsch; Alfred Hobisch
Journal:  Urology       Date:  2003-07       Impact factor: 2.649

3.  Secondary carcinoma of the penis; a review of the literature and a report of nine new cases.

Authors:  A J PAQUIN; S I ROLAND
Journal:  Cancer       Date:  1956 May-Jun       Impact factor: 6.860

4.  EAU guidelines on penile cancer: 2014 update.

Authors:  Oliver W Hakenberg; Eva M Compérat; Suks Minhas; Andrea Necchi; Chris Protzel; Nick Watkin
Journal:  Eur Urol       Date:  2014-11-01       Impact factor: 20.096

5.  Extensive cutaneous metastasis of transitional cell carcinoma of the bladder.

Authors:  Yavuz Akman; Kamil Cam; Ayse Kavak; Murat Alper
Journal:  Int J Urol       Date:  2003-02       Impact factor: 3.369

6.  Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report.

Authors:  Nurettin Cem Sönmez; Burhan Coşkun; Serdar Arisan; Soner Güney; Ayhan Dalkiliç
Journal:  Cases J       Date:  2009-08-14

Review 7.  Secondary neoplasms of the urinary system and male genital organs.

Authors:  Doriana Morichetti; Roberta Mazzucchelli; Antonio Lopez-Beltran; Liang Cheng; Marina Scarpelli; Ziya Kirkali; Francesco Montorsi; Rodolfo Montironi
Journal:  BJU Int       Date:  2009-07-14       Impact factor: 5.588

Review 8.  Transitional cell carcinoma of the bladder metastatic to the penis.

Authors:  Kevin P Bordeau; Donald F Lynch
Journal:  Urology       Date:  2004-05       Impact factor: 2.649

9.  Secondary penile tumours revisited.

Authors:  Jacob Cherian; Sreekumar Rajan; Ali Thwaini; Yaser Elmasry; Tariq Shah; Rajiv Puri
Journal:  Int Semin Surg Oncol       Date:  2006-10-11

Review 10.  Metastatic tumors of the penis: a report of 8 cases and review of the literature.

Authors:  Ke Zhang; Jun Da; Hai-Jun Yao; Da-Chao Zheng; Zhi-Kang Cai; Yue-Qing Jiang; Ming-Xi Xu; Zhong Wang
Journal:  Medicine (Baltimore)       Date:  2015-01       Impact factor: 1.889

  10 in total

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