Literature DB >> 28093819

Investigation of the quasi-simultaneous arrival (QSA) effect on a CAMECA IMS 7f-GEO.

Clive Jones1, David A Fike1, Paula Peres2.   

Abstract

RATIONALE: IMS 7f-GEO isotope ratio applications increasingly involve analyses (e.g., S- or O- isotopes, coupled with primary ion currents <30 pA) for which quasi-simultaneous arrival (QSA) could compromise precision and accuracy of data. QSA and associated correction have been widely investigated for the CAMECA NanoSIMS instruments, but not for the IMS series.
METHODS: Sulfur and oxygen isotopic ratio experiments were performed using an electron multiplier (EM) detector, employing Cs+ primary ion currents of 1, 2, 5 and 11.5 pA (nominal) and a variety of secondary ion transmissions to vary QSA probability. An experiment to distinguish between QSA undercounting and purported aperture-related mass fractionation was performed using an EM for 16 O- and 18 O- plus an additional 16 O- measurement using a Faraday cup (FC) detector. An experiment to investigate the accuracy of the QSA correction was performed by comparing S isotopic ratios obtained using an EM with those obtained on the same sample using dual FCs.
RESULTS: The QSA effect was observed on the IMS-7f-GEO, and QSA coefficients (β) of ~0.66 were determined, in agreement with reported NanoSIMS measurements, but different from the value (0.5) predicted using Poisson statistics. Aperture-related fractionation was not sufficient to explain the difference but uncertainties in primary ion flux measurement could play a role. When QSA corrected, the isotope ratio data obtained using the EM agreed with the dual FC data, within statistical error.
CONCLUSIONS: QSA undercounting could compromise isotope ratio analyses requiring ~1 × 105 counts per second for the major isotope and primary currents <20 pA. The error could be >8‰ for a 1 pA primary current. However, correction can be accurately applied. For instrumental mass fractionation (IMF)-corrected data, the magnitude of the error resulting from not correcting for QSA is dependent on the difference in secondary ion count rate between the unknown and standard analyses.
Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Entities:  

Year:  2017        PMID: 28093819     DOI: 10.1002/rcm.7828

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN: 0951-4198            Impact factor:   2.419


  2 in total

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Authors:  Michael S Guzman; Karthikeyan Rengasamy; Michael M Binkley; Clive Jones; Tahina Onina Ranaivoarisoa; Rajesh Singh; David A Fike; J Mark Meacham; Arpita Bose
Journal:  Nat Commun       Date:  2019-03-22       Impact factor: 14.919

2.  Direct Observation of the Dynamics of Single-Cell Metabolic Activity during Microbial Diauxic Growth.

Authors:  H L O McClelland; C Jones; L M Chubiz; D A Fike; A S Bradley
Journal:  mBio       Date:  2020-03-03       Impact factor: 7.867

  2 in total

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