Literature DB >> 2809361

[Composite tissue (bone and ligaments) allografts in the reconstruction of the posterior element of the canine spine (preliminary report)].

T Yamaguchi1, H Yamamoto, Y Kamioka.   

Abstract

Reconstructions of the posterior element of the spine with allograft transplantation in adult mongrel dogs were studied histologically. The bone and ligament composite allografts were frozen at -80 degrees for reduction of the antigenicity. Within four weeks, a new bone formation was observed, and the bony union was completed at 8 weeks after the grafting. The transplanted lamina was replaced by the newly formed bone by creeping substitution within 32 weeks. However a part of the spinous process was absorbed, and was not replaced by new bone. The supraspinal ligament and the ligamentum flavum were gradually replaced by connective tissue resembling a ligament. The scar tissue did not invade into the spinal canal, and symptoms of myelopathy did not appear throughout the observation. Although a biomechanical investigation was not performed, these results indicated reconstruction of the posterior element of the spine with allograft transplantation is possible for clinical application.

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Year:  1989        PMID: 2809361

Source DB:  PubMed          Journal:  Nihon Seikeigeka Gakkai Zasshi        ISSN: 0021-5325


  1 in total

1.  Freeze-dried fibular allograft in anterior spinal surgery: cervical and lumbar applications.

Authors:  F T Wetzel; M A Hoffman; R R Arcieri
Journal:  Yale J Biol Med       Date:  1993 May-Jun
  1 in total

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