| Literature DB >> 2809361 |
T Yamaguchi1, H Yamamoto, Y Kamioka.
Abstract
Reconstructions of the posterior element of the spine with allograft transplantation in adult mongrel dogs were studied histologically. The bone and ligament composite allografts were frozen at -80 degrees for reduction of the antigenicity. Within four weeks, a new bone formation was observed, and the bony union was completed at 8 weeks after the grafting. The transplanted lamina was replaced by the newly formed bone by creeping substitution within 32 weeks. However a part of the spinous process was absorbed, and was not replaced by new bone. The supraspinal ligament and the ligamentum flavum were gradually replaced by connective tissue resembling a ligament. The scar tissue did not invade into the spinal canal, and symptoms of myelopathy did not appear throughout the observation. Although a biomechanical investigation was not performed, these results indicated reconstruction of the posterior element of the spine with allograft transplantation is possible for clinical application.Entities:
Mesh:
Year: 1989 PMID: 2809361
Source DB: PubMed Journal: Nihon Seikeigeka Gakkai Zasshi ISSN: 0021-5325