| Literature DB >> 28093544 |
David Safronetz1,2, Nafomon Sogoba3, Sory Ibrahim Diawara3, Sidy Bane3, Kyle Rosenke4, Ousmane Maiga3, Matt Boisen5, Robert F Garry6, Luis M Branco5, L Robbin Lindsay1,2, Sékou F Traoré3, Heinz Feldmann1,4, Seydou Doumbia3.
Abstract
AbstractPreviously, we reported a high seroprevalence rate of Lassa virus antibodies in inhabitants of three villages in southern Mali where infected rodents have been demonstrated. Herein, we report a 1-year follow-up study in which we were able to collect a second blood samples from 88.7% of participants of the same cohort. We identified 23 seroconversions for IgG antibodies reactive against Lassa virus, representing an incidence of 6.3% (95% confidence interval = 3.8-8.8%). Seroconversion was frequently seen in preteenage children (12/23, 51.7%) and two household/familial clusters were identified. These results confirm active transmission of Lassa virus is occurring in southern Mali and appropriate diagnostic testing should be established for this etiological agent of severe viral hemorrhagic fever.Entities:
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Year: 2017 PMID： 28093544 PMCID： PMC5392646 DOI： 10.4269/ajtmh.16-0821
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345