Yen-Ching Chen1,2,3, Chien-Cheng Jung1, Jen-Hau Chen1,4, Jeng-Min Chiou5, Ta-Fu Chen6, Ya-Fang Chen7, Sung-Chun Tang6, Shin-Joe Yeh6, Meei-Shyuan Lee8. 1. Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan. 2. Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan. 3. Research Center for Genes, Environment, and Human Health, College of Public Health, National Taiwan University, Taipei, Taiwan. 4. Department of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan. 5. Institute of Statistical Science, Academia Sinica, Taipei, Taiwan. 6. Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan. 7. Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan. 8. Department of Public Health, School of Public Health, National Defense Medical College, Taipei, Taiwan.
Abstract
BACKGROUND: Significant differences exist between eastern and western diets, and the way in which Chinese dietary intake relates to specific cognitive domains remains unclear. We aimed to assess the association between dietary patterns (DPs) and cognitive decline in Chinese elderly. SETTING: Participants were recruited from the elderly health checkup program of a teaching hospital in Taipei, Taiwan. PARTICIPANTS: A total of 475 elders (age ≥65) were included in this prospective cohort study. MEASUREMENTS: The outcome comprised the decline of global and domain-specific cognition between baseline (2011-2013) and follow-up (2013-2015). Dietary data from the previous year were collected via a food frequency questionnaire at baseline, and a factor analysis was performed to identify DPs. Multivariable linear regression and logistic regression models were used to assess associations between Chinese DPs and cognitive decline over 2 years adjusting for selected covariates. RESULTS: Three DPs (vegetable, meat, and traditional) were identified. Moderate- or high-score "vegetable" DP significantly protected against decline of logical memory (recall I: β = 0.16-0.18, odds ratio (OR) = 0.42-0.48; recall II: β = 0.17-0.21); while high-score DP increased executive function decline (β = -0.22). A high-score "meat" DP was related to decline of verbal fluency-total score (β = -0.19); while moderate- or high-score "meat" DP protected against attention decline (β = 0.20-0.22). High-score "traditional" DP protected against decline of logical memory-recall I (β = 0.18). No significant association was observed for global cognition. CONCLUSION: These findings suggest that three DPs identified in Chinese elderly were associated with different cognitive domains. Further research is needed to explore the efficacy of dietary interventions in reducing cognitive decline in older adults.
BACKGROUND: Significant differences exist between eastern and western diets, and the way in which Chinese dietary intake relates to specific cognitive domains remains unclear. We aimed to assess the association between dietary patterns (DPs) and cognitive decline in Chinese elderly. SETTING:Participants were recruited from the elderly health checkup program of a teaching hospital in Taipei, Taiwan. PARTICIPANTS: A total of 475 elders (age ≥65) were included in this prospective cohort study. MEASUREMENTS: The outcome comprised the decline of global and domain-specific cognition between baseline (2011-2013) and follow-up (2013-2015). Dietary data from the previous year were collected via a food frequency questionnaire at baseline, and a factor analysis was performed to identify DPs. Multivariable linear regression and logistic regression models were used to assess associations between Chinese DPs and cognitive decline over 2 years adjusting for selected covariates. RESULTS: Three DPs (vegetable, meat, and traditional) were identified. Moderate- or high-score "vegetable" DP significantly protected against decline of logical memory (recall I: β = 0.16-0.18, odds ratio (OR) = 0.42-0.48; recall II: β = 0.17-0.21); while high-score DP increased executive function decline (β = -0.22). A high-score "meat" DP was related to decline of verbal fluency-total score (β = -0.19); while moderate- or high-score "meat" DP protected against attention decline (β = 0.20-0.22). High-score "traditional" DP protected against decline of logical memory-recall I (β = 0.18). No significant association was observed for global cognition. CONCLUSION: These findings suggest that three DPs identified in Chinese elderly were associated with different cognitive domains. Further research is needed to explore the efficacy of dietary interventions in reducing cognitive decline in older adults.
Authors: Joseph Firth; Nicola Veronese; Jack Cotter; Nitin Shivappa; James R Hebert; Carolyn Ee; Lee Smith; Brendon Stubbs; Sarah E Jackson; Jerome Sarris Journal: Front Psychiatry Date: 2019-05-15 Impact factor: 4.157
Authors: Joost A Agelink van Rentergem; Nathalie R de Vent; Ben A Schmand; Jaap M J Murre; Janneke P C Staaks; Hilde M Huizenga Journal: Neuropsychol Rev Date: 2020-02-01 Impact factor: 7.444