| Literature DB >> 28091918 |
A I Osip'yants1,2, E N Knyazev1,2, A V Galatenko1, K M Nyushko2, V V Galatenko1, M Yu Shkurnikov3, B Ya Alekseev2.
Abstract
We performed diagnostic classification of plasma specimens from patients with non-metastatic and metastatic prostate cancer based on pairs of miRNA that have no individual diagnostic significance. Of 230 miRNA detected in plasma specimens, 3 pairs were diagnostically significant. The miRNA pair hsa-miR-19b-3p and hsa-miR-297 demonstrated highest sensitivity and specificity. Among common target genes of these miRNA, CFL2 gene associated with cell mobility was detected.Entities:
Keywords: blood plasma; little invasive diagnosis; miRNA; prostate cancer
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Year: 2017 PMID： 28091918 DOI： 10.1007/s10517-017-3620-6
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804