Literature DB >> 28090613

Expedient and modular access to 2-azabicyclic architectures by iron-catalyzed dehydrative coupling of alcohol-bearing allylic lactams.

Katie Hovenkotter1, Hannah Braunstein1, Spencer Langevin1, Timothy K Beng1.   

Abstract

A high-yielding, cost-effective, modular and environmentally benign approach to [5,5]- or [6,5]-2-azabicyclic architectures bearing vicinal stereocenters, by Fe-catalyzed intramolecular dehydrative coupling of readily affordable alcohol-bearing allylic lactams is presented.

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Year:  2017        PMID： 28090613     DOI： 10.1039/c6ob02652d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Stereocontrolled access to δ-lactone-fused-γ-lactams bearing angular benzylic quaternary stereocenters.

Authors:  Timothy K Beng; Morgan J Rodriguez; Claire Borg
Journal:  RSC Adv       Date:  2022-06-14       Impact factor: 4.036

2.  Site-selective, catalytic, and diastereoselective sp3 C-H hydroxylation and alkoxylation of vicinally functionalized lactams.

Authors:  Timothy K Beng; Victoria Shearer; Rachel Davey; Ivianne Redman
Journal:  RSC Adv       Date:  2020-05-27       Impact factor: 4.036

3.  Modular synthesis and transition metal-free alkynylation/alkenylation of Castagnoli-Cushman-derived N,O- and N,S-heterocyclic vinyl chlorides.

Authors:  Timothy K Beng; Abdikani Omar Farah; Victoria Shearer
Journal:  RSC Adv       Date:  2020-10-07       Impact factor: 4.036
  3 in total

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