Literature DB >> 28089214

Prevalence of chronic pancreatitis: Results of a primary care physician-based population study.

Gabriele Capurso1, Livia Archibugi2, Piera Pasquali3, Alessandro Aceti4, Paolo Balducci4, Patrizia Bianchi5, Francesco Buono5, Stefano Camerucci4, Rosanna Cantarini4, Sergio Centofanti3, Patrizia Colantonio4, Riccarda Cremaschi5, Sergio Crescenzi5, Caterina Di Mauro4, Davide Di Renzi4, Andrea Filabozzi3, Alfonso Fiorillo4, Giuseppe Giancaspro4, Paola Giovannetti4, Giuseppe Lanna6, Claudio Medori4, Emilio Merletti6, Enzo Nunnari3, Francesca Paris6, Marco Pavone3, Angela Piacenti3, Almerindo Rossi3, Maria Cristina Scamuffa4, Giovanni Spinelli5, Marco Taborchi6, Biagio Valente4, Antonella Villanova3, Alberto Chiriatti3, Gianfranco Delle Fave2.   

Abstract

BACKGROUND: Data on chronic pancreatitis prevalence are scanty and usually limited to hospital-based studies. AIM: Investigating chronic pancreatitis prevalence in primary care.
METHODS: Participating primary care physicians reported the prevalence of chronic pancreatitis among their registered patients, environmental factors and disease characteristics. The data were centrally reviewed and chronic pancreatitis cases defined according to M-ANNHEIM criteria for diagnosis and severity and TIGAR-O classification for etiology.
RESULTS: Twenty-three primary care physicians participated in the study. According to their judgment, 51 of 36.401 patients had chronic pancreatitis. After reviewing each patient data, 11 turned out to have definite, 5 probable, 19 borderline and 16 uncertain disease. Prevalence was 30.2/100.000 for definite cases and 44.0/100.000 for definite plus probable cases. Of the 16 patients with definite/probable diagnosis, 8 were male, with mean age of 55.6 (±16.7). Four patients had alcoholic etiology, 5 post-acute/recurrent pancreatitis, 6 were deemed to be idiopathic. Four had pancreatic exocrine insufficiency, 10 were receiving pancreatic enzymes, and six had pain. Most patients had initial stage and non-severe disease.
CONCLUSIONS: This is the first study investigating the prevalence of chronic pancreatitis in primary care. Results suggest that the prevalence in this context is higher than in hospital-based studies, with specific features, possibly representing an earlier disease stage.
Copyright © 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Chronic pancreatitis; Etiology; Pancreatic exocrine insufficiency; Prevalence; Primary care

Mesh:

Year:  2016        PMID: 28089214     DOI: 10.1016/j.dld.2016.12.024

Source DB:  PubMed          Journal:  Dig Liver Dis        ISSN: 1590-8658            Impact factor:   4.088


  6 in total

1.  Prevalence of primary painless chronic pancreatitis: A systematic review and meta-analysis.

Authors:  Furqan A Bhullar; Mahya Faghih; Venkata S Akshintala; Ahmed I Ahmed; Katie Lobner; Elham Afghani; Anna E Phillips; Phil A Hart; Mitchell L Ramsey; Benjamin L Bick; Louise Kuhlmann; Asbjørn M Drewes; Dhiraj Yadav; Søren S Olesen; Vikesh K Singh
Journal:  Pancreatology       Date:  2021-11-18       Impact factor: 3.996

2.  Vitamins D and K as Factors Associated with Osteopathy in Chronic Pancreatitis: A Prospective Multicentre Study (P-BONE Study).

Authors:  Serena Stigliano; Alexander Waldthaler; Emma Martinez-Moneo; Luana Lionetto; Stuart Robinson; Marko Malvik; Aleksandra Hedstrom; Aleksandra Kaczka; Marius Scholdei; Stephan Haas; Maurizio Simmaco; Gianfranco Delle Fave; Matthias Lohr; Peter Simon; Gabriele Capurso
Journal:  Clin Transl Gastroenterol       Date:  2018-10-15       Impact factor: 4.488

3.  Pancreatitis: TIGAR-O Version 2 Risk/Etiology Checklist With Topic Reviews, Updates, and Use Primers.

Authors:  David C Whitcomb
Journal:  Clin Transl Gastroenterol       Date:  2019-06       Impact factor: 4.488

4.  Acute and Chronic Pancreatitis Disease Prevalence, Classification, and Comorbidities: A Cohort Study of the UK BioBank.

Authors:  Daniel M Spagnolo; Phil J Greer; Celeste Shelton Ohlsen; Shannon Mance; Mitchell Ellison; Cameron Breze; Ben Busby; David C Whitcomb; Mark Haupt
Journal:  Clin Transl Gastroenterol       Date:  2022-01-19       Impact factor: 4.396

5.  Time trends in incidence and prevalence of chronic pancreatitis: A 25-year population-based nationwide study.

Authors:  Søren S Olesen; Laust H Mortensen; Elisabeth Zinck; Ulrik Becker; Asbjørn M Drewes; Camilla Nøjgaard; Srdan Novovic; Dhiraj Yadav; Janne S Tolstrup
Journal:  United European Gastroenterol J       Date:  2021-02-22       Impact factor: 4.623

Review 6.  Molecular mechanisms of pancreatic myofibroblast activation in chronic pancreatitis and pancreatic ductal adenocarcinoma.

Authors:  Andrew Cannon; Christopher Michael Thompson; Rakesh Bhatia; Katharine Anne Armstrong; Joyce Christopher Solheim; Sushil Kumar; Surinder Kumar Batra
Journal:  J Gastroenterol       Date:  2021-07-19       Impact factor: 6.772

  6 in total

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