Literature DB >> 28085002

HCV intergenotype 2k/1b recombinant detected in a DAA-treated patient in Italy.

Stefania Paolucci1, Marta Premoli1, Serena Ludovisi2, Mario U Mondelli2,3, Fausto Baldanti1,4.   

Abstract

Direct-acting antiviral (DAA) combinations are potent and effective drugs currently recommended for treatment of chronic HCV infection. Difficult to treat genotypes are the most important predictors of treatment failure. We report a case of DAA treatment failure in an HCV-infected patient carrying a recombinant genotype 2k/1b. This strain, first isolated from a Russian patient in 2002, has now been observed for the first time in Italy.

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Year:  2017        PMID： 28085002     DOI： 10.3851/IMP3130

Source DB:  PubMed          Journal:  Antivir Ther        ISSN： 1359-6535


  2 in total

1.  First identification of a recombinant form of hepatitis C virus in Austrian patients by full-genome next generation sequencing.

Authors:  Evelyn Stelzl; Bernhard Haas; Bernd Bauer; Sherry Zhang; Ellen H Fiss; Grantland Hillman; Aaron T Hamilton; Rochak Mehta; Marintha L Heil; Ed G Marins; Brigitte I Santner; Harald H Kessler
Journal:  PLoS One       Date:  2017-07-25       Impact factor: 3.240

2.  Hepatitis C virus genotype 1 and 2 recombinant genomes and the phylogeographic history of the 2k/1b lineage.

Authors:  Reilly Hostager; Manon Ragonnet-Cronin; Ben Murrell; Charlotte Hedskog; Anu Osinusi; Simone Susser; Christoph Sarrazin; Evguenia Svarovskaia; Joel O Wertheim
Journal:  Virus Evol       Date:  2019-10-09
  2 in total

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