Literature DB >> 28083598

[Drug treatment of dementia].

J W Kraft1.   

Abstract

The number of patients with dementia continues to increase worldwide, mainly due to the demographic developments. Early diagnosis and individualized therapy offers the chance of healing in secondary dementias. The therapy of the more common primary neurodegenerative forms is able to improve the course of the disease. As part of a multimodal management the therapy of dementias includes pharmacological treatment, nondrug treatment strategies, and psychosocial interventions. The treatment is administered depending on dementia form and stage. Antidementive medication and differentiated pharmacological therapy of frequent mental and behavioral symptoms corresponding to current guidelines contribute decisively to stabilize quality of life and activities of daily living, delaying the progression, and thus improving the care situation of patients and caregivers.

Entities:  

Keywords:  Behavioral symptoms; Cholinesterase inhibitors; Ginkgo biloba; Memantine; Mental disorders

Mesh:

Substances:

Year:  2017        PMID: 28083598     DOI: 10.1007/s00108-016-0180-1

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  16 in total

1.  Behavioural and psychological symptoms of dementia: a seven-tiered model of service delivery.

Authors:  Henry Brodaty; Brian M Draper; Lee-Fay Low
Journal:  Med J Aust       Date:  2003-03-03       Impact factor: 7.738

Review 2.  Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014.

Authors:  L S Schneider; F Mangialasche; N Andreasen; H Feldman; E Giacobini; R Jones; V Mantua; P Mecocci; L Pani; B Winblad; M Kivipelto
Journal:  J Intern Med       Date:  2014-03       Impact factor: 8.989

3.  Risk of death in elderly users of conventional vs. atypical antipsychotic medications.

Authors:  Philip S Wang; Sebastian Schneeweiss; Jerry Avorn; Michael A Fischer; Helen Mogun; Daniel H Solomon; M Alan Brookhart
Journal:  N Engl J Med       Date:  2005-12-01       Impact factor: 91.245

4.  Potentially inappropriate medications in the elderly: the PRISCUS list.

Authors:  Stefanie Holt; Sven Schmiedl; Petra A Thürmann
Journal:  Dtsch Arztebl Int       Date:  2010-08-09       Impact factor: 5.594

Review 5.  Apathy in Dementia: Systematic Review of Recent Evidence on Pharmacological Treatments.

Authors:  Fleur Harrison; Liesbeth Aerts; Henry Brodaty
Journal:  Curr Psychiatry Rep       Date:  2016-11       Impact factor: 5.285

6.  Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease.

Authors:  O L Lopez; J T Becker; A S Wahed; J Saxton; R A Sweet; D A Wolk; W Klunk; S T Dekosky
Journal:  J Neurol Neurosurg Psychiatry       Date:  2009-02-09       Impact factor: 10.154

7.  [Prevalence of dementia and medical care in German nursing homes: a nationally representative survey].

Authors:  Martina Schäufele; Leonore Köhler; Ingrid Hendlmeier; Andreas Hoell; Siegfried Weyerer
Journal:  Psychiatr Prax       Date:  2013-05-13

8.  Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial.

Authors:  Pierre N Tariot; Martin R Farlow; George T Grossberg; Stephen M Graham; Scott McDonald; Ivan Gergel
Journal:  JAMA       Date:  2004-01-21       Impact factor: 56.272

Review 9.  Economic considerations in the management of Alzheimer's disease.

Authors:  Carolyn W Zhu; Mary Sano
Journal:  Clin Interv Aging       Date:  2006       Impact factor: 4.458

Review 10.  Interventions to delay functional decline in people with dementia: a systematic review of systematic reviews.

Authors:  Kate Laver; Suzanne Dyer; Craig Whitehead; Lindy Clemson; Maria Crotty
Journal:  BMJ Open       Date:  2016-04-27       Impact factor: 2.692

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