Zhuoxin Peng1, Shengnan Wang1, Biao Xu1, Weibing Wang2. 1. Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China. 2. Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China. Electronic address: wwb@fudan.edu.cn.
Abstract
OBJECTIVE: To identify the barriers to and enablers of the prevention of mother-to-child transmission (PMTCT) of HIV program in China. METHODS: A systematic review of the existing literature regarding barriers to and enablers of the implementation of the PMTCT program in China was performed. The checklist from the SURE guidelines (Supporting the Use of Research Evidence) was used to synthesize the barriers and enablers (supporting strategies) and to analyze their relationships. The HIV testing rate, vertical transmission rate, and antiretroviral treatment (ART) acceptance rate among HIV-infected women and their infants was also extracted from the included studies to assess the effectiveness of the enablers. RESULTS: Initially 794 publications were identified, and ultimately 14 articles were included. Eighteen types of barrier and nine types of supportive strategy were identified, mainly at the level of social and political issues, healthcare recipients, healthcare providers, and the healthcare system. Based on government-oriented multi-sector cooperation, enablers in China have included community-hospital-family promotion, comprehensive financial support for service recipients, free HIV testing at marriage registration, the opt-out model, and the one-to-one service model. CONCLUSIONS: Experience in China suggests that the government's role in coordination and the acceptability and accessibility of the service should be the primary concerns in regard to the PMTCT project.
OBJECTIVE: To identify the barriers to and enablers of the prevention of mother-to-child transmission (PMTCT) of HIV program in China. METHODS: A systematic review of the existing literature regarding barriers to and enablers of the implementation of the PMTCT program in China was performed. The checklist from the SURE guidelines (Supporting the Use of Research Evidence) was used to synthesize the barriers and enablers (supporting strategies) and to analyze their relationships. The HIV testing rate, vertical transmission rate, and antiretroviral treatment (ART) acceptance rate among HIV-infectedwomen and their infants was also extracted from the included studies to assess the effectiveness of the enablers. RESULTS: Initially 794 publications were identified, and ultimately 14 articles were included. Eighteen types of barrier and nine types of supportive strategy were identified, mainly at the level of social and political issues, healthcare recipients, healthcare providers, and the healthcare system. Based on government-oriented multi-sector cooperation, enablers in China have included community-hospital-family promotion, comprehensive financial support for service recipients, free HIV testing at marriage registration, the opt-out model, and the one-to-one service model. CONCLUSIONS: Experience in China suggests that the government's role in coordination and the acceptability and accessibility of the service should be the primary concerns in regard to the PMTCT project.
Authors: Aggrey D Mukose; Senait Kebede; Christine Muhumuza; Fredrick Makumbi; Henry Komakech; Esther Bayiga; Denis Busobozi; Joshua Musinguzi; Andreas Kuznik; Peter Stegman; Steven Forsythe; Joseph Kagaayi Journal: Biomed Res Int Date: 2020-05-18 Impact factor: 3.411