Matteo Bassetti1, Alessia Carnelutti, Daniele Muser, Elda Righi, Nicola Petrosillo, Fernando Di Gregorio, Thomas J Werner, Abass Alavi. 1. aInfectious Diseases Division, Santa Maria Misericordia University Hospital bCardiovascular Medicine Division, Santa Maria Misericordia University Hospital, Udine cNational Institute for Infectious Diseases Lazzaro Spallanzani-INMI IRCCS, Rome dNuclear Medicine Division, Santa Maria Misericordia University Hospital, Udine, Italy eDivision of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Abstract
PURPOSE OF REVIEW: 18F-Fluorodeoxyglucose positron emission tomography/computed tomography is a well-established technique for diagnosis and management of a number of neoplastic conditions. However, in recent years the body of literature regarding its potential role in infectious diseases has progressively increased, with promising results. RECENT FINDINGS: So far 18F-fluorodeoxyglucose positron emission tomography/computed tomography has a well-established role and is recommended by guidelines only in a few settings, such as prosthetic valve endocarditis, vascular device infections, and chronic osteomyelitis. However, even the lack of large, prospective randomized trials, an increasing number of small series and case reports suggest a potential role in the diagnosis, disease staging, and monitoring of treatment response of several other infective conditions. SUMMARY: In this article, we summarize the available evidence and potential future applications of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis and management of infectious diseases.
PURPOSE OF REVIEW: 18F-Fluorodeoxyglucose positron emission tomography/computed tomography is a well-established technique for diagnosis and management of a number of neoplastic conditions. However, in recent years the body of literature regarding its potential role in infectious diseases has progressively increased, with promising results. RECENT FINDINGS: So far 18F-fluorodeoxyglucose positron emission tomography/computed tomography has a well-established role and is recommended by guidelines only in a few settings, such as prosthetic valve endocarditis, vascular device infections, and chronic osteomyelitis. However, even the lack of large, prospective randomized trials, an increasing number of small series and case reports suggest a potential role in the diagnosis, disease staging, and monitoring of treatment response of several other infective conditions. SUMMARY: In this article, we summarize the available evidence and potential future applications of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis and management of infectious diseases.
Authors: Stephen D Zoller; Howard Y Park; Tove Olafsen; Charles Zamilpa; Zachary Dc Burke; Gideon Blumstein; William L Sheppard; Christopher D Hamad; Kellyn R Hori; Jen-Chieh Tseng; Julie Czupryna; Craig McMannus; Jason T Lee; Mafalda Bispo; Francisco Romero Pastrana; Elisa Jm Raineri; Jeffery F Miller; Lloyd S Miller; Jan Maarten van Dijl; Kevin P Francis; Nicholas M Bernthal Journal: JCI Insight Date: 2019-02-07
Authors: Howard Y Park; Stephen D Zoller; Vishal Hegde; William Sheppard; Zachary Burke; Gideon Blumstein; Christopher Hamad; Marina Sprague; John Hoang; Ryan Smith; Francisco Romero Pastrana; Julie Czupryna; Lloyd S Miller; Marina López-Álvarez; Mafalda Bispo; Marleen van Oosten; Jan Maarten van Dijl; Kevin P Francis; Nicholas M Bernthal Journal: Sci Rep Date: 2021-01-15 Impact factor: 4.379