Literature DB >> 28079592

Implementation science: the laboratory as a command centre.

Debrah I Boeras1, John N Nkengasong, Rosanna W Peeling.   

Abstract

PURPOSE OF REVIEW: Recent advances in point-of-care technologies to ensure universal access to affordable quality-assured diagnostics have the potential to transform patient management, surveillance programmes, and control of infectious diseases. Decentralization of testing can put tremendous stresses on fragile health systems if the laboratory is not involved in the planning, introduction, and scale-up strategies. RECENT
FINDINGS: The impact of investments in novel technologies can only be realized if these tests are evaluated, adopted, and scaled up within the healthcare system with appropriate planning and understanding of the local contexts in which these technologies will be used.
SUMMARY: In this digital age, the laboratory needs to take on the role of the Command Centre for technology introduction and implementation. Implementation science is needed to understand the political, cultural, economic, and behavioural context for technology introduction. The new paradigm should include: building a comprehensive system of laboratories and point-of-care testing sites to provide quality-assured diagnostic services with good laboratory-clinic interface to build trust in test results and linkage to care; building and coordinating a comprehensive national surveillance and communication system for disease control and global health emergencies; conducting research to monitor the impact of new tools and interventions on improving patient care.

Entities:  

Mesh:

Year:  2017        PMID: 28079592     DOI: 10.1097/COH.0000000000000349

Source DB:  PubMed          Journal:  Curr Opin HIV AIDS        ISSN: 1746-630X            Impact factor:   4.283


  5 in total

Review 1.  The future of viral hepatitis testing: innovations in testing technologies and approaches.

Authors:  Rosanna W Peeling; Debrah I Boeras; Francesco Marinucci; Philippa Easterbrook
Journal:  BMC Infect Dis       Date:  2017-11-01       Impact factor: 3.090

Review 2.  Improving the Accessibility and Efficiency of Point-of-Care Diagnostics Services in Low- and Middle-Income Countries: Lean and Agile Supply Chain Management.

Authors:  Desmond Kuupiel; Vitalis Bawontuo; Tivani P Mashamba-Thompson
Journal:  Diagnostics (Basel)       Date:  2017-11-29

3.  Formative research to inform development of a new diagnostic for soil-transmitted helminths: Going beyond the laboratory to ensure access to a needed product.

Authors:  Helen L Storey; Neha Agarwal; Jason Cantera; Allison Golden; Kerry Gallo; Tara Herrick; Vicente Belizario; Jimmy Kihara; Charles Mwandawiro; Bill Cadwallader; Tala de Los Santos
Journal:  PLoS Negl Trop Dis       Date:  2019-05-31

Review 4.  REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes.

Authors:  Kevin J Land; Debrah I Boeras; Xiang-Sheng Chen; Andrew R Ramsay; Rosanna W Peeling
Journal:  Nat Microbiol       Date:  2018-12-13       Impact factor: 17.745

5.  Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal.

Authors:  Yakou Dieye; Helen L Storey; Kelsey L Barrett; Emily Gerth-Guyette; Laura Di Giorgio; Allison Golden; Dunia Faulx; Michael Kalnoky; Marie Khemesse Ngom Ndiaye; Ngayo Sy; Malang Mané; Babacar Faye; Mamadou Sarr; Elhadji Mamadou Dioukhane; Roger B Peck; Philippe Guinot; Tala de Los Santos
Journal:  PLoS Negl Trop Dis       Date:  2017-10-03
  5 in total

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